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Chapter and Conference Paper
Swin UNETR for Tumor and Lymph Node Segmentation Using 3D PET/CT Imaging: A Transfer Learning Approach
Delineation of Gross Tumor Volume (GTV) is essential for the treatment of cancer with radiotherapy. GTV contouring is a time-consuming specialized manual task performed by radiation oncologists. Deep Learning ...
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Chapter and Conference Paper
Deep Learning and Radiomics Based PET/CT Image Feature Extraction from Auto Segmented Tumor Volumes for Recurrence-Free Survival Prediction in Oropharyngeal Cancer Patients
Aim: The development and evaluation of deep learning (DL) and radiomics based models for recurrence-free survival (RFS) prediction in oropharyngeal squamous cell carcinoma (OPSCC) patients based on clinical fe...
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Article
Open AccessDaily dose evaluation based on corrected CBCTs for breast cancer patients: accuracy of dose and complication risk assessment
The goal of this study is to validate different CBCT correction methods to select the superior method that can be used for dose evaluation in breast cancer patients with large anatomical changes treated with p...
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Chapter and Conference Paper
Self-supervised Multi-modality Image Feature Extraction for the Progression Free Survival Prediction in Head and Neck Cancer
Long-term survival of oropharyngeal squamous cell carcinoma patients (OPSCC) is quite poor. Accurate prediction of Progression Free Survival (PFS) before treatment could make identification of high-risk patien...
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Article
Open AccessApplications of various range shifters for proton pencil beam scanning radiotherapy
A range pull-back device, such as a machine-related range shifter (MRS) or a universal patient-related range shifter (UPRS), is needed in pencil beam scanning technique to treat shallow tumors.
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Article
Open AccessEvaluation of a 3D surface imaging system for deep inspiration breath-hold patient positioning and intra-fraction monitoring
To determine the accuracy of a surface guided radiotherapy (SGRT) system for positioning of breast cancer patients in breath-hold (BH) with respect to cone-beam computed tomography (CBCT). Secondly, to evaluat...
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Chapter
Lower Gastrointestinal Malignancies
Lower GI cancers present a particular problem for multidisciplinary care. Concurrent chemoradiotherapy is the standard of care, but with it comes a host of treatment-related toxicities. For rectal cancer, preo...
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Chapter
Salivary Gland Tumors
Salivary gland malignancies are uncommon, representing 1–6% of head and neck malignancies and 0.3% of all cancers (55% occur in parotid gland, 30% in submandibular gland, 10–15% in the sublingual and minor sal...
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Chapter
Sarcoma
Radiation therapy plays an integral role in sarcoma management. Proton therapy with its advantageous dose distribution provides the potential for dose escalation and reduced integral dose and normal tissue rad...
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Chapter
Proton Treatment Planning
The differences between planning proton-beam therapy and photon-beam therapy derive from the differences in the physics of protons and photons, namely [1]:
That protons have a f...
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Article
Open AccessAn in-silico comparison of proton beam and IMRT for postoperative radiotherapy in completely resected stage IIIA non-small cell lung cancer
Post-operative radiotherapy (PORT) for stage IIIA completely-resected non-small cell lung cancer (CR-NSCLC) has been shown to improve local control; however, it is unclear that this translates into a survival ...
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Article
Open AccessAcute gastrointestinal and genitourinary toxicity of image-guided intensity modulated radiation therapy for prostate cancer using a daily water-filled endorectal balloon
Our purpose was to report acute gastrointestinal (GI) and genitourinary (GU) toxicity rates for prostate cancer patients undergoing image-guided intensity modulated radiation therapy (IG-IMRT) with a daily end...
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Article
Open AccessPrimary treatment of acromegaly with high-dose lanreotide: a case series
The first-line treatment for acromegaly is transsphenoidal surgery. In approximately 50% of patients, however, a cure is not possible with surgery and alternatives are needed. Somatostatin analog therapy is th...
