8 Result(s)
within
Stefan Bauer
Biomedicine, general
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Article
Causal machine learning for predicting treatment outcomes
Causal machine learning (ML) offers flexible, data-driven methods for predicting treatment outcomes including efficacy and toxicity, thereby supporting the assessment and safety of drugs. A key benefit of caus...
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Article
Open AccessOvercoming barriers to data sharing with medical image generation: a comprehensive evaluation
Privacy concerns around sharing personally identifiable information are a major barrier to data sharing in medical research. In many cases, researchers have no interest in a particular individual’s information...
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Article
Open AccessAdjuvant formulated virus-like particles expressing native-like forms of the Lassa virus envelope surface glycoprotein are immunogenic and induce antibodies with broadly neutralizing activity
Lassa mammarenavirus (LASV) is a rodent-borne arenavirus endemic to several West African countries. It is the causative agent of human Lassa fever, an acute viral hemorrhagic fever disease. To date, no therapeuti...
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Article
Automatic Scan Planning for Magnetic Resonance Imaging of the Knee Joint
Automatic scan planning for magnetic resonance imaging of the knee aims at defining an oriented bounding box around the knee joint from sparse scout images in order to choose the optimal field of view for the ...
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Article
Toll-erating self DNA
Discrimination between self and bacterial DNA has been attributed in part to differential modification of prokaryotic and eukaryotic DNA. However, cellular localization of innate DNA receptors may be even more...
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Article
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease
Autoimmune diabetes mellitus in humans is characterized by immunological destruction of pancreatic beta islet cells. We investigated the circumstances under which CD8+ T cells specific for pancreatic beta-islet a...
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Article
Human TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848
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Article
Crystal structure of the murine NK cell–activating receptor NKG2D at 1.95 Å
NKG2D, a homodimeric lectin-like receptor, is a unique stimulatory molecule that is found on natural killer cells, T cells and activated macrophages. The natural ligands for murine NKG2D are distant major hist...
