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Article
Related disorders of bone
Renal osteodystrophy includes a broad spectrum of abnormalities in bone and mineral metabolism. This review article discusses related bone disorders, including calcific uremic arteriolopathy, “osteoporosis” an...
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Chapter
Mineral Metabolism in Health and Disease
Parathyroid hormone (PTH) is an 84 amino acid peptide (mol. wt.: 9500) secreted by the parathyroid gland. Except for possible ectopic production in certain neoplastic syndromes, the parathyroid is the only kno...
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Chapter
The Effects of Calcium on ADH Action in Cortical Collecting Tubules Perfused In Vitro
The effects of calcium on ADH action have been the object of intense study for 20 years (1). Extreme elevations in serosal calcium (Ca++) concentration (10 mM) have been shown to block ADH-induced water flow in t...
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Chapter
Calcium transport in the kidney
Calcium is reabsorbed in most segments of the mammalian nephron in a pattern generally similar to that of sodium reabsorption. Of the filtered load, 50%–60% is reabsorbed in the proximal convoluted tubule, whe...
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Chapter
Mineral Metabolism in Health and Disease
The elucidation of the metabolism of vitamin D has increased our understanding of mineral homeostasis. Vitamin D is produced in the skin as cholecalciferol (vitamin D3) and is absorbed in the small bowel as both ...
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Chapter
The Effects of Parathyroid Hormone on Renal Phosphate Handling
Parathyroid hormone (PTH) has been known to produce phosphaturia in a variety of species (Agus et al., 1971; Amiel et al., 1970; Bell et al., 1972). This response is most strikingly demonstrated in individuals wi...
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Article
Studies of malformation syndromes of man XIB: the cerebro-hepato-renal syndrome of zellweger: Comparative pathology
A study of 11 autopsied cases of the cerebro-hepato-renal syndrome of Zellweger (ZS) is reported. All cases had severe, peristent congenital hypotonia, hepatic lobular disarray, renal cortical cysts and pulmon...
