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    Article

    Selective inhibition of the BD2 bromodomain of BET proteins in prostate cancer

    Proteins of the bromodomain and extra-terminal (BET) domain family are epigenetic readers that bind acetylated histones through their bromodomains to regulate gene transcription. Dual-bromodomain BET inhibitor...

    Emily J. Faivre, Keith F. McDaniel, Daniel H. Albert, Srinivasa R. Mantena… in Nature (2020)