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  1. Article

    Open Access

    TDP-43 pathology disrupts nuclear pore complexes and nucleocytoplasmic transport in ALS/FTD

    The cytoplasmic mislocalization and aggregation of TAR DNA-binding protein-43 (TDP-43) is a common histopathological hallmark of the amyotrophic lateral sclerosis and frontotemporal dementia disease spectrum (...

    Ching-Chieh Chou, Yi Zhang, Mfon E. Umoh, Spencer W. Vaughan… in Nature Neuroscience (2018)

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