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Article

Tuning IL-2 signaling by ADP-ribosylation of CD25

Control of immunologic tolerance and homeostasis rely on Foxp3⁺CD4⁺CD25⁺ regulatory T cells (Tregs) that constitutively express the high affinity receptor for Interleukin-2, CD25. Tregs proliferate in response to...

Sophie Teege, Alexander Hann, Maria Miksiewicz, Cary MacMillan… in Scientific Reports (2015)