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  1. Article

    Open Access

    Comparison of microbial signatures between paired faecal and rectal biopsy samples from healthy volunteers using next-generation sequencing and culturomics

    Faecal samples are frequently used to characterise the gut microbiota in health and disease, yet there is considerable debate about how representative faecal bacterial profiles are of the overall gut community...

    Indrani Mukhopadhya, Jennifer C. Martin, Sophie Shaw, Aileen J. McKinley in Microbiome (2022)

  2. Article

    Open Access

    Comparative transcriptomics and host-specific parasite gene expression profiles inform on drivers of proliferative kidney disease

    The myxozoan parasite, Tetracapsuloides bryosalmonae has a two-host life cycle alternating between freshwater bryozoans and salmonid fish. Infected fish can develop Proliferative Kidney Disease, characterised by ...

    Marc Faber, Sophie Shaw, Sohye Yoon, Eduardo de Paiva Alves, Bei Wang in Scientific Reports (2021)

  3. Article

    Open Access

    Fetal androgen exposure is a determinant of adult male metabolic health

    Androgen signalling is a critical driver of male development. Fetal steroid signalling can be dysregulated by a range of environmental insults and clinical conditions. We hypothesised that poor adult male heal...

    Katarzyna J. Siemienowicz, Panagiotis Filis, Sophie Shaw in Scientific Reports (2019)

  4. No Access

    Article

    Quantification of ethyl glucuronide, ethyl sulfate, nicotine, and its metabolites in human fetal liver and placenta

    Tobacco and alcohol use during pregnancy is serious public health concerns and result in adverse developmental outcomes. Identifying in utero exposure is often achieved through meconium analysis or via materna...

    Madeleine J. Swortwood, Sarah H. Bartock, Karl B. Scheidweiler in Forensic Toxicology (2018)