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Article
Open AccessNarcotics information management system in South Korea: system development and innovation
As the misuse and abuse of medical narcotics are increasing in South Korea, an information system for the integrated information management of medical narcotic drugs across the nation is needed. This paper pre...
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Article
Open AccessRisk of aortic aneurysm and aortic dissection with the use of fluoroquinolones in Korea: a nested case–control study
Recent studies have raised concern about the association of fluoroquinolones with an increased risk of aortic aneurysm and aortic dissection. We aimed to evaluate such risk in a Korean population.
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Article
Open AccessRisk Management for the 21st Century: Current Status and Future Needs
Global adoption of risk management principles outlined in the International Conference on Harmonisation (ICH) E2E guideline and the Council for International Organizations of Medical Sciences (CIOMS) Working G...
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Article
OECD validation of the rodent Hershberger assay using three reference chemicals; 17α-methyltestosterone, procymidone, and p,p′-DDE
The rodent Hershberger assay is being validated as an in vivo test method for detecting androgenic or antiandrogenic compounds by the Organization for Economic Cooperation and Development (OECD). As part of th...
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Article
Repeated 28-day oral toxicity study of ketoconazole in rats based on the draft protocol for the “Enhanced OECD Test Guideline No. 407” to detect endocrine effects
We performed a 28-day repeated-dose toxicity study of ketoconazole, a widely used an antimycotic drug, based on the draft protocol of the “Enhanced OECD Test Guideline 407” (Enhanced TG407) to investigate whet...
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Article
Repeated 28-day oral toxicity study of vinclozolin in rats based on the draft protocol for the “Enhanced OECD Test Guideline No. 407” to detect endocrine effects
We performed a 28-day repeated-dose toxicity study of vinclozolin, a widely used fungicide, based on the draft protocol of the “Enhanced OECD Test Guideline 407” (Enhanced TG407) to investigate whether vincloz...
