9 Result(s)
within
Sonia Tarazona
Life Sciences
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Article
A multi-omic study for uncovering molecular mechanisms associated with hyperammonemia-induced cerebellar function impairment in rats
Patients with liver cirrhosis may develop covert or minimal hepatic encephalopathy (MHE). Hyperammonemia (HA) and peripheral inflammation play synergistic roles in inducing the cognitive and motor alterations ...
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Article
Open AccesstappAS: a comprehensive computational framework for the analysis of the functional impact of differential splicing
Recent advances in long-read sequencing solve inaccuracies in alternative transcript identification of full-length transcripts in short-read RNA-Seq data, which encourages the development of methods for isofor...
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Article
Open AccessRGmatch: matching genomic regions to proximal genes in omics data integration
The integrative analysis of multiple genomics data often requires that genome coordinates-based signals have to be associated with proximal genes. The relative location of a genomic region with respect to the ...
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Open AccessErratum to: A survey of best practices for RNA-seq data analysis
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Open AccessA survey of best practices for RNA-seq data analysis
RNA-sequencing (RNA-seq) has a wide variety of applications, but no single analysis pipeline can be used in all cases. We review all of the major steps in RNA-seq data analysis, including experimental design, ...
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Article
Open AccessRNAseq analysis of Aspergillus fumigatus in blood reveals a just wait and see resting stage behavior
Invasive aspergillosis is started after germination of Aspergillus fumigatus conidia that are inhaled by susceptible individuals. Fungal hyphae can grow in the lung through the epithelial tissue and disseminate h...
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Article
Open AccessUnderstanding disease mechanisms with models of signaling pathway activities
Understanding the aspects of the cell functionality that account for disease or drug action mechanisms is one of the main challenges in the analysis of genomic data and is on the basis of the future implementa...
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Open AccessPathway network inference from gene expression data
The development of high-throughput omics technologies enabled genome-wide measurements of the activity of cellular elements and provides the analytical resources for the progress of the Systems Biology discipl...
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Open AccessFunctional assessment of time course microarray data
Time-course microarray experiments study the progress of gene expression along time across one or several experimental conditions. Most developed analysis methods focus on the clustering or the differential ex...
