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Article
Open AccessGenome sequencing of evolved aspergilli populations reveals robust genomes, transversions in A. flavus, and sexual aberrancy in non-homologous end-joining mutants
Aspergillus spp. comprises a very diverse group of lower eukaryotes with a high relevance for industrial applications and clinical implications. These multinucleate species are often cultured for many generations...
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Article
Open AccessRNAseq analysis of Aspergillus fumigatus in blood reveals a just wait and see resting stage behavior
Invasive aspergillosis is started after germination of Aspergillus fumigatus conidia that are inhaled by susceptible individuals. Fungal hyphae can grow in the lung through the epithelial tissue and disseminate h...
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Protocol
Gene Deletion in Candida albicans Wild-Type Strains Using the SAT1-Flip** Strategy
Targeted gene inactivation is an important method to investigate gene function. In the diploid yeast Candida albicans, the generation of homozygous knock-out mutants requires the sequential replacement of both al...