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    IL4Rα and IL17A Blockade Rescue Autoinflammation in SOCS1 Haploinsufficiency

    By inhibition of JAK-STAT signaling, SOCS1 acts as a master regulator of the cytokine response across numerous tissue types and cytokine pathways. Haploinsufficiency of SOCS1 has recently emerged as a monogeni...

    Conor Gruber, Angelica Lee, Sofija Buta, Saakshi Khattri… in Journal of Clinical Immunology (2023)