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  1. Article

    Open Access

    Nutrient shortage triggers the hexosamine biosynthetic pathway via the GCN2-ATF4 signalling pathway

    The hexosamine biosynthetic pathway (HBP) is a nutrient-sensing metabolic pathway that produces the activated amino sugar UDP-N-acetylglucosamine, a critical substrate for protein glycosylation. Despite its bi...

    Cédric Chaveroux, Carmen Sarcinelli, Virginie Barbet, Sofiane Belfeki in Scientific Reports (2016)