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Article
Cloning, expression and nucleotide sequences of two xylanase genes from Paenibacillus sp.
Two genes, xynA and xynB, encoding xylanases from Paenibacillus sp. KCTC 8848P were cloned and expressed in Escherichia coli, and their nucleotide sequences were determined. The xylanases of E. coli transformants...
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Article
Inhibition of HIV-1 reverse transcriptase and HIV-1 integrase and antiviral activity of Korean seaweed extracts
Forty-seven species of marine macroalgae from the coast of Korea havebeen screened for the presence of inhibitory compounds against humanimmunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and HIV...
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Article
Open AccessPartial rescue of the Na+-Ca2+ exchanger (NCX1) knock-out mouse by transgenic expression of NCX1
The null mutation of cardiac Na+-Ca2+ exchanger (NCX1) gene in mice caused death of embryo in utero at embryonic day (ED) 9.0-9.5 and this embryonic lethality appears resulted from abnormal heart development. In ...
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Article
Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation
Histone modification through acetylation and deacetylation is a key process in transcription, DNA replication, and chromosome segregation. During mitosis, histones are highly acetylated and chromatin is conden...
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Article
Open AccessElevated matrix metalloproteinase-9 in patients with systemic sclerosis
Matrix metalloproteinase-9 (MMP-9) has been implicated in the pathogenesis of cancer, autoimmune disease, and various pathologic conditions characterized by excessive fibrosis. In this study, we investigated t...
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Article
Decreased incidence of hepatic veno-occlusive disease and fewer hemostatic derangements associated with intravenous busulfan vs oral busulfan in adults conditioned with busulfan + cyclophosphamide for allogeneic bone marrow transplantation
We investigated the occurrence of hepatic veno-occlusive disease (VOD) after allogeneic bone marrow transplantation (BMT) in 241 adults conditioned with busulfan + cyclophosphamide at a single institute and re...
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Chapter and Conference Paper
Sentence Segmentation Model to Improve Tree Annotation Tool
In this paper, we propose a sentence segmentation model for a semi-automatic tree annotation tool using a parsing model. For the purpose of improving both parsing performance and parsing complexity without any...
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Article
On-chip Escherichia coli culture, purification, and detection of expressed proteins
In a recent study, we reported the results of a rapid high-throughput expression analysis of the affinity-tagged proteins present in total cell lysates, using a surface plasmon resonance (SPR) imaging protein ...
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Article
Increased ethylene and decreased phenolic compounds stimulate somatic embryo regeneration in leaf thin section cultures ofDoritaenopsis hybrid
The effects of endogenous levels of ethylene and phenolic compounds on somatic embryogenesis, medium-browning, and peroxidase activity were evaluated in thin section cultures ofDoritaenopsis. Cultures were mainta...
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Article
Effect of molecular chaperones on the soluble expression of alginate lyase inE. coli
When the alginate lyase gene (aly) fromPseudoalteromonas elyakovii was expressed inE. coli, most of the gene product was organized as aggregated insoluble particles known as inclusion bodies. To examine the effec...
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Article
Gene–gene interaction between IL-13 and IL-13Rα1 is associated with total IgE in Korean children with atopic asthma
Interleukin (IL)-13, which is essential for IgE synthesis, mediates its effects by binding with a receptor composed of IL-4Rα and IL-13Rα1. We investigated the effects of IL-13 and IL-13Rα1 polymorphisms in Ko...
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Chapter and Conference Paper
Performance Evaluation of the Optimal Hierarchy for Cellular Networks
Reducing the location update cost has been a critical research issue since the location update process requires heavy signaling traffics. One of the solutions is employing the hierarchical structure in cellula...
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Chapter and Conference Paper
Development and Application of Gd2O3:Eu3+ Nano Phosphor for High Resolution Digital X-ray Imaging System
In this paper, we investigated the imaging characteristic of Eu3+-doped Gd2O3 nano phosphor for high resolution digital x-ray imaging system. The Gd2O3:Eu3+ nano particles were synthesized using a low temperature...
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Article
Two forms of Vibrio vulnificus metalloprotease VvpE are secreted via the type II general secretion system
Vibrio vulnificus has been known to secrete one form of metalloprotease VvpE (45 kDa) that is cleaved to 34 kDa-VvpE and 11 kDa-C-terminal propeptide via extracellular autoproteolysis. Ho...
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Article
Is E/E′ reliable in patients with regional wall motion abnormalities to estimate left ventricular filling pressure?
Background There is limited data on the diagnostic utility of the transmitral to mitral annular velocity (E/E′) by tissue Doppler imaging (TDI) in the presence of regional wall motion abnormalities (RWMA). We aim...
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Article
Open AccessSoluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying mechanisms are not clear. In this study, we investigated the mechanisms of the immunoregulatory activity of MSCs on T cel...
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Article
Modulation of osteocalcin expression by purmorphamine derivatives
Purmorphamine is a purine analog and it affects osteogenesis, in part, through the modulation of Sonic Hedgehog signaling pathway. However, the underlying mechanism has remained elusive. Previously, we identif...
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Article
Anti-allergic effects of white rose petal extract and anti-atopic properties of its hexane fraction
Rosa rugosa is a species of rose native to eastern Asia. The root of R. rugosa has been used to treat diabetes mellitus, pain and chronic inflammatory disease, and a R. rugosa petal extra...
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Article
Open AccessAcupuncture for persistent allergic rhinitis: a multi-centre, randomised, controlled trial protocol
Allergic rhinitis is one of the most common health complaints worldwide. Complementary and alternative medical approaches have been employed to relieve allergic rhinitis symptoms and to avoid the side effects ...
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Article
Enhanced cytotoxicity of 5-FU by bFGF through up-regulation of uridine phosphorylase 1
Anti cancer agent 5-FU (Fluoro Uracil) is a prodrug that can be metabolized and then activated to interfere with RNA and DNA homeostasis. However, the majority of administered 5-FU is known to be catabolized in v...
