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    Article

    Inhibition of histone deacetylase activity increases chromosomal instability by the aberrant regulation of mitotic checkpoint activation

    Histone modification through acetylation and deacetylation is a key process in transcription, DNA replication, and chromosome segregation. During mitosis, histones are highly acetylated and chromatin is conden...

    Hyun-** Shin, Kwan-Hyuck Baek, Ae-Hwa Jeon, So-Jung Kim, Kyung-Lib Jang in Oncogene (2003)

  2. Article

    Open Access

    Acupuncture for persistent allergic rhinitis: a multi-centre, randomised, controlled trial protocol

    Allergic rhinitis is one of the most common health complaints worldwide. Complementary and alternative medical approaches have been employed to relieve allergic rhinitis symptoms and to avoid the side effects ...

    Jong-In Kim, Myeong Soo Lee, So-Young Jung, Jun-Yong Choi, Sanghoon Lee in Trials (2009)

  3. Article

    Open Access

    Alcohol consumption and carotid artery structure in Korean adults aged 50 years and older

    Epidemiologic studies of the association between alcohol consumption and carotid artery structure have reported conflicting results. We investigated the association between alcohol consumption and carotid athe...

    Young-Hoon Lee, Min-Ho Shin, Sun-Seog Kweon, Sung-Woo Choi in BMC Public Health (2009)

  4. Article

    Open Access

    Acupuncture for dry eye: a randomised controlled trial protocol

    Dry eye is usually managed by conventional medical interventions such as artificial tears, anti-inflammatory drugs and surgical treatment. However, since dry eye is one of the most frequent ophthalmologic diso...

    Tae-Hun Kim, Jong-In Kim, Mi-Suk Shin, Myeong Soo Lee, Jun-Yong Choi in Trials (2009)

  5. Article

    Open Access

    Acupuncture for dry eye: a multicentre randomised controlled trial with active comparison intervention (artificial tear drop) using a mixed method approach protocol

    Previous studies of acupuncture show favourable results for both subjective and objective outcomes of dry eye. However, firm conclusions could not be drawn from these studies because the quality of the trials ...

    Tae-Hun Kim, Jung Won Kang, Kun Hyung Kim, Kyung-Won Kang, Mi-Suk Shin in Trials (2010)

  6. Article

    Open Access

    Cumulative smoking exposure, duration of smoking cessation, and peripheral arterial disease in middle-aged and older Korean men

    We investigated the association of cumulative smoking exposure and duration of smoking cessation with peripheral arterial disease (PAD).

    Young-Hoon Lee, Min-Ho Shin, Sun-Seog Kweon, **-Su Choi, Jung-Ae Rhee in BMC Public Health (2011)

  7. Article

    Open Access

    Evaluation of wet-cup** therapy for persistent non-specific low back pain: a randomised, waiting-list controlled, open-label, parallel-group pilot trial

    Persistent non-specific low back pain (PNSLBP) is one of the most frequently experienced types of back pain around the world. Wet-cup** is a common intervention for various pain conditions, especially in Kor...

    Jong-In Kim, Tae-Hun Kim, Myeong Soo Lee, Jung Won Kang, Kun Hyung Kim in Trials (2011)

  8. Article

    Open Access

    Association of smoking status, cumulative smoking, duration of smoking cessation, age of starting smoking, and depression in Korean adults

    Many previous studies did not sufficiently control for several confounding factors that may affect the association between smoking and depression, such as socioeconomic status. We investigated the association ...

    Woo-Jun Yun, Min-Ho Shin, Sun-Seog Kweon, So-Yeon Ryu, Jung-Ae Rhee in BMC Public Health (2012)

  9. Article

    Open Access

    Efficacy of moxibustion for pre- or stage I hypertension: study protocol for a pilot randomized controlled trial

    Hypertension is a risk factor for cardiovascular disease, and the prevalence of hypertension tends to increase with age. Current treatments for hypertension have adverse side effects and poor adherence. The pu...

    Kyung-Min Shin, Ji-Eun Park, Yan Liu, Hee-Jung Jung, So-Young Jung, Min-Hee Lee in Trials (2012)

  10. Article

    Open Access

    An open-label study of effects of acupuncture on chronic fatigue syndrome and idiopathic chronic fatigue: study protocol for a randomized controlled trial

    Even though chronic fatigue syndrome and idiopathic chronic fatigue are quite common, there are no clearly known causes. Most treatments are therefore symptomatic in nature, and chronic fatigue syndrome and id...

    Jung-Eun Kim, Kwon-Eui Hong, Hyeong-Jun Kim, **-Bong Choi, Yong-Hyeon Baek in Trials (2013)

  11. Article

    Open Access

    Electroacupuncture to treat painful diabetic neuropathy: study protocol for a three-armed, randomized, controlled pilot trial

    The purpose of this study is to conduct a basic analysis of the effectiveness and safety of electroacupuncture in the treatment of painful diabetic neuropathy (PDN) as compared to placebo and usual care and to...

    Seunghoon Lee, Joo-Hee Kim, Kyung-Min Shin, Jung-Eun Kim, Tae-Hun Kim in Trials (2013)

  12. Article

    Open Access

    Electroacupuncture for chemotherapy-induced peripheral neuropathy: study protocol for a pilot multicentre randomized, patient-assessor-blinded, controlled trial

    Chemotherapy-induced peripheral neuropathy (CIPN) is the main dose-limiting side effect of neurotoxic chemotherapeutic agents. CIPN can lead not only to loss of physical function, difficulties in activities of...

    Joo-Hee Kim, Eun-Jung Kim, Byung-Kwan Seo, Sanghun Lee, Seunghoon Lee in Trials (2013)

  13. Article

    Open Access

    Auricular acupuncture for prehypertension and stage 1 hypertension: study protocol for a pilot multicentre randomised controlled trial

    Hypertension, a worldwide public health problem, is a major risk factor for cardiovascular and kidney disease, and the medical and economic burden of hypertension is increasing. Auricular acupuncture has been ...

    Joo-Hee Kim, Hyun Jung Jung, Tae-Hun Kim, Seunghoon Lee, Jung-Eun Kim in Trials (2013)

  14. Article

    Open Access

    Household and area income levels are associated with smoking status in the Korean adult population

    Some previous studies have suggested that area-level characteristics have effects on smoking. The aim of this study was to evaluate the associations between household income and area income on smoking in Korea...

    Woo-Jun Yun, Jung-Ae Rhee, Sun A Kim, Sun-Seog Kweon, Young-Hoon Lee in BMC Public Health (2015)

  15. Article

    Effects of Oxytocin on Neural Response to Facial Expressions in Patients with Schizophrenia

    Impaired facial emotion recognition is a core deficit in schizophrenia. Oxytocin has been shown to improve social perception in patients with schizophrenia; however, the effect of oxytocin on the neural activi...

    Na Young Shin, Hye Yoon Park, Wi Hoon Jung, ** Woo Park in Neuropsychopharmacology (2015)

  16. Article

    Open Access

    Acupuncture for chronic fatigue syndrome and idiopathic chronic fatigue: a multicenter, nonblinded, randomized controlled trial

    The causes of chronic fatigue syndrome (CFS) and idiopathic chronic fatigue (ICF) are not clearly known, and there are no definitive treatments for them. Therefore, patients with CFS and ICF are interested in ...

    Jung-Eun Kim, Byung-Kwan Seo, **-Bong Choi, Hyeong-Jun Kim, Tae-Hun Kim in Trials (2015)

  17. Article

    Erratum: Effects of Oxytocin on Neural Response to Facial Expressions in Patients with Schizophrenia

    Correction to: Neuropsychopharmacology advance online publication 4 March 2015; doi:10.1038/npp.2015.41 In this article, the correct affiliation for So-Yeon Kim is Department of Psychology, Duksung Women’s Uni...

    Na Young Shin, Hye Yoon Park, Wi Hoon Jung, ** Woo Park in Neuropsychopharmacology (2015)

  18. Article

    Open Access

    A multi-center, randomized controlled clinical trial, cost-effectiveness and qualitative research of electroacupuncture with usual care for patients with non-acute pain after back surgery: study protocol for a randomized controlled trial

    Although pain after back surgery is known to be difficult to control, various treatment options are available to patients and physicians. A protocol for a confirmatory randomized controlled trial (RCT) on pain...

    Byung-Cheul Shin, Jae-Heung Cho, In-Hyuk Ha, In Heo, Jun-Hwan Lee, Koh-Woon Kim in Trials (2018)

  19. Article

    Open Access

    The efficacy and safety of the herbal medicine geonchildan for patients with active rheumatoid arthritis: study protocol for a randomized, double-blind, placebo-controlled, parallel pilot trial

    This study aims to assess the efficacy and safety of geonchildan, a Korean traditional herbal medicine, for patients with active rheumatoid arthritis (RA) and evaluate the feasibility of a large-scale confirmator...

    Seunghoon Lee, Yeeun Cho, Jihye Kim, Jung Won Kang, Ga Young Yoon, Jun-Hwan Lee in Trials (2018)

  20. Article

    Open Access

    Visit-to-visit systolic blood pressure variability in patients with ST-elevation myocardial infarction predicts long-term cardiovascular outcomes

    Elevated visit-to-visit blood pressure variability (BPV), independent of mean BP, has been associated with cardiovascular events. However, its impact after ST-elevation myocardial infarction (STEMI) has not be...

    Moon-Seung Soh, **-Sun Park, Kyoung-Woo Seo in Journal of Human Hypertension (2019)