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Article
Open AccessDisruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI) treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System, that dasatinib is associa...
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Article
Open AccessCell shape information is transduced through tension-independent mechanisms
The shape of a cell within tissues can represent the history of chemical and physical signals that it encounters, but can information from cell shape regulate cellular phenotype independently? Using optimal co...
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Article
Open AccessA biomimetic gelatin-based platform elicits a pro-differentiation effect on podocytes through mechanotransduction
Using a gelatin microbial transglutaminase (gelatin-mTG) cell culture platform tuned to exhibit stiffness spanning that of healthy and diseased glomeruli, we demonstrate that kidney podocytes show marked stiff...
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Reference Work Entry In depth
Laser-Based Micromachining
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Living Reference Work Entry In depth
Laser-Based Micromachining
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Reference Work Entry In depth
Laser Based Micromachining