-
Article
The Qing’s central government response to the most severe drought over the past 300 years
The Dingwu Great Famine (DGF) is considered to be the worst drought in China over the past 300 years. How the central government took steps to cope with the catastrophe during this period and ultimately surviv...
-
Article
The Mixed Blessing of Leaders’ Artificial Intelligence (AI)-oriented Change Behavior: Implications for Employee Job Performance and Unethical Behavior
The rapid development of artificial intelligence (AI) has led many companies to embrace AI-oriented changes; leaders’ AI-oriented change behaviors have therefore become increasingly prevalent in contemporary o...
-
Article
Impact of corporate carbon emission reduction on financing constraints
The carbon emission reduction behaviour of enterprises is a crucial element for achieving the “double-carbon” target. Based on the panel data of China’s Shanghai and Shenzhen A-share nonfinancial listed compan...
-
Article
Immunotherapy for the treatment of advanced nasopharyngeal carcinoma: a promising new era
Nasopharyngeal carcinoma (NPC) is ranked the top otorhinolaryngology malignant tumors in the world. However, the general prognosis of recurrent and metastatic (R/M) nasopharyngeal carcinomas (NPCs) remains poo...
-
Article
Knowledge map** of planetary boundaries based on bibliometrics analysis
The planetary boundaries concept has triggered a vast amount of pure and applied scientific research, as well as policy and governance activities globally. Indeed, it has rapidly become a centerpiece of sustai...
-
Article
Open AccessHierarchical dynamic convolutional neural network for laryngeal disease classification
Laryngeal disease classification is a relatively hard task in medical image processing resulting from its complex structures and varying viewpoints in data collection. Some existing methods try to tackle this ...
-
Article
Enhanced thermoelectric performance of single-walled carbon nanotubes films assembled with aniline tetramer
Although single-walled carbon nanotubes (SWCNTs) had potential application in self-powered systems for wearable thermoelectric devices due to their light weight, flexibility, and high conductivity, how to impr...
-
Article
Open AccessAppropriate dose of intravitreal ranibizumab for ROP: a retrospective study
To compare the recurrence rate of retinopathy of prematurity (ROP) after treatment with 0.3 mg vs. 0.25 mg ranibizumab.
-
Article
Open AccessPopulation-scale analysis of common and rare genetic variation associated with hearing loss in adults
To better understand the genetics of hearing loss, we performed a genome-wide association meta-analysis with 125,749 cases and 469,497 controls across five cohorts. We identified 53/c loci affecting hearing lo...
-
Article
Open AccessA multiepitope vaccine encoding four Eimeria epitopes with PLGA nanospheres: a novel vaccine candidate against coccidiosis in laying chickens
With a worldwide distribution, Eimeria spp. could result in serious economic losses to the poultry industry. Due to drug resistance and residues, there are no ideal drugs and vaccines against Eimeria spp. in food...
-
Chapter and Conference Paper
The Peer Support for Elderly Breast Cancer Patients’ Continuing Care at Home Through Smart Service System
Breast cancer is the first most frequent cancer and cancer with the highest incidence and the most frequent cancer among women globally
-
Article
Open AccessPharmacokinetic herb-drug interactions between Aidi injection and doxorubicin in rats with diethylnitrosamine-induced hepatocellular carcinoma
Aidi Injection (ADI), a Chinese herbal preparation with anti-cancer activity, is used for the treatment of hepatocellular carcinoma (HCC). Several clinical studies have shown that co-administration of ADI with...
-
Article
Detection of Geochemical Element Assemblage Anomalies Using a Local Correlation Approach
As direct prospecting data, geochemical data play an important role in modelling prospect potential. Geochemical element assemblage anomalies are usually reflected by the correlation between elements. Correlat...
-
Article
Open AccessA prognostic model for elderly patients with squamous non-small cell lung cancer: a population-based study
Squamous cell carcinoma (SCC) is a main pathological type of non-small cell lung cancer. It is common among elderly patients with poor prognosis. We aimed to establish an accurate nomogram to predict survival ...
-
Article
Open AccessRisk factors for renal failure and short-term prognosis in patients with spontaneous intracerebral haemorrhage complicated by acute kidney injury
Although acute kidney injury (AKI) is a known risk factor for adverse clinical outcomes in patients with spontaneous intracerebral haemorrhage (SICH), little is known about the predisposing factors that contri...
-
Article
Simultaneous Determination of Five Components of Laportea bulbifera Extract in Rat Plasma by LC-MS/MS: Application to a Pharmacokinetic Study
Laportea bulbifera (Siebold & Zucc.) Wedd., Urticaceae, is a medicinal herb customarily used by the Miao people in China, for the treatment of rheumatism, traumatic injury, and other symptoms. The aim of this stu...
-
Article
Open AccessSELEX tool: a novel and convenient gel-based diffusion method for monitoring of aptamer-target binding
Aptamers, single-stranded DNAs or RNAs, can be selected from a library containing random sequences using a method called Systematic Evolution of Ligands by EXponential Enrichment (SELEX). In SELEX, monitoring ...
-
Article
Transgelin-2 expression in breast cancer and its relationships with clinicopathological features and patient outcome
Transgelin-2 is an actin-binding protein that is widely expressed in various tissues and organs of the body, and reportedly may participate in the development and progression of multiple cancers. However, the ...
-
Article
Open AccessExome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Protein-coding genetic variants that strongly affect disease risk can yield relevant clues to disease pathogenesis. Here we report exome-sequencing analyses of 20,791 individuals with type 2 diabetes (T2D) and...
-
Article
Associations of vitamin K status with mortality and cardiovascular events in peritoneal dialysis patients
Vitamin K deficiency, expressed by a high level of desphospho-uncarboxylated matrix GLA protein (dp-ucMGP), is highly prevalent in dialysis patients. However, the predictive ability of the vitamin K status rem...
