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  1. Article

    Open Access

    Estimation of tumor cell total mRNA expression in 15 cancer types predicts disease progression

    Single-cell RNA sequencing studies have suggested that total mRNA content correlates with tumor phenotypes. Technical and analytical challenges, however, have so far impeded at-scale pan-cancer examination of ...

    Shaolong Cao, Jennifer R. Wang, Shuangxi Ji, Peng Yang, Yaoyi Dai in Nature Biotechnology (2022)