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    Chapter

    The Role of Neuropilin-1/Semaphorin 3A Signaling in Lymphatic Vessel Development and Maturation

    During development, the lymphatic and the blood vascular system form highly branched networks that show extensive architectural similarities with the peripheral nervous system. Increasing evidence suggests tha...

    Alexandra M. Ochsenbein, Sinem Karaman in Developmental Aspects of the Lymphatic Vas… (2014)

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    Article

    Decline of lymphatic vessel density and function in murine skin during aging

    Lymphatic vessels play important roles in the pathogenesis of many conditions that have an increased prevalence in the elderly population. However, the effects of the aging process on the lymphatic system are ...

    Sinem Karaman, Dorina Buschle, Paola Luciani, Jean-Christophe Leroux in Angiogenesis (2015)

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    Open Access

    Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling

    Lymphatic vessels play important roles in fluid drainage and in immune responses, as well as in pathological processes including cancer progression and inflammation. While the molecular regulation of the earli...

    Alexandra M. Ochsenbein, Sinem Karaman, Steven T. Proulx, Rhea Goldmann in Angiogenesis (2016)