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Article
Open AccessIncreasing The Genetic Admixture of Available Lines of Human Pluripotent Stem Cells
Human pluripotent stem cells (hPSCs) may significantly improve drug development pipeline, serving as an in vitro system for the identification of novel leads, and for testing drug toxicity. Furthermore, these cel...
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Article
Open AccessThe segregation of different submicroscopic imbalances underlying the clinical variability associated with a familial karyotypically balanced translocation
About 7 % of karyotypically balanced chromosomal rearrangements (BCRs) are associated with congenital anomalies due to gene or regulatory element disruption, and cryptic imbalances on rearranged chromosomes. R...
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Use of Human Embryonic Stem Cells in Therapy
Pluripotent stem cells (PSCs) are defined by their potential of unlimited self-renewal and the ability to differentiate – both in vitro and in vivo – into all cell types of endodermal, mesodermal and ectodermal o...