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  1. Article

    Open Access

    HIV- 1 lentivirus tethering to the genome is associated with transcription factor binding sites found in genes that favour virus survival

    Lentiviral vectors (LV) are attractive for permanent and effective gene therapy. However, integration into the host genome can cause insertional mutagenesis highlighting the importance of understanding of LV i...

    Saqlain Suleman, Annette Payne, Johnathan Bowden, Sharmin Al Haque in Gene Therapy (2022)

  2. Article

    Open Access

    Production of lentiviral vectors using novel, enzymatically produced, linear DNA

    The manufacture of large quantities of high-quality DNA is a major bottleneck in the production of viral vectors for gene therapy. Touchlight Genetics has developed a proprietary abiological technology that ad...

    Rajvinder Karda, John R. Counsell, Kinga Karbowniczek, Lisa J. Caproni in Gene Therapy (2019)