3 Result(s)
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Article
Open AccessJoint eQTL assessment of whole blood and dura mater tissue from individuals with Chiari type I malformation
Expression quantitative trait loci (eQTL) play an important role in the regulation of gene expression. Gene expression levels and eQTLs are expected to vary from tissue to tissue, and therefore multi-tissue an...
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Article
Open AccessFine map** of a linkage peak with integration of lipid traits identifies novel coronary artery disease genes on chromosome 5
Coronary artery disease (CAD), and one of its intermediate risk factors, dyslipidemia, possess a demonstrable genetic component, although the genetic architecture is incompletely defined. We previously reporte...
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Article
Open AccessSNPs in Multi-Species Conserved Sequences (MCS) as useful markers in association studies: a practical approach
Although genes play a key role in many complex diseases, the specific genes involved in most complex diseases remain largely unidentified. Their discovery will hinge on the identification of key sequence varia...
