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Article
Open AccessProbing local innate immune responses after mucosal immunisation
Intranasal immunisation is potentially a very effective route for inducing both mucosal and systemic immunity to an infectious agent.
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Article
C13orf31 (FAMIN) is a central regulator of immunometabolic function
Variants of the human gene C13orf31 (LACC1) are associated with various disease risks. Kaser and colleagues identify a role for the protein encoded (called ‘FAMIN’) in regulating macrophage fatty-acid oxidation a...
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Article
High-throughput phenoty** reveals expansive genetic and structural underpinnings of immune variation
By develo** a high-density murine immunophenoty** platform compatible with high-throughput genetic screening, we have established profound contributions of genetics and structure to immune variation ( ...