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    Article

    Metabotropic action of postsynaptic kainate receptors triggers hippocampal long-term potentiation

    The authors show that activation of GluK2-containing kainate receptors on hippocampal neurons, by either agonist application or high-frequency synaptic stimulation, leads to a new form of NMDA-receptor-indepen...

    Milos M Petrovic, Silvia Viana da Silva, James P Clement in Nature Neuroscience (2017)

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    Open Access

    Early synaptic deficits in the APP/PS1 mouse model of Alzheimer’s disease involve neuronal adenosine A2A receptors

    Synaptic plasticity in the autoassociative network of recurrent connections among hippocampal CA3 pyramidal cells is thought to enable the storage of episodic memory. Impaired episodic memory is an early manif...

    Silvia Viana da Silva, Matthias Georg Haberl, Pei Zhang in Nature Communications (2016)

  3. Article

    Open Access

    An anterograde rabies virus vector for high-resolution large-scale reconstruction of 3D neuron morphology

    Glycoprotein-deleted rabies virus (RABV ∆G) is a powerful tool for the analysis of neural circuits. Here, we demonstrate the utility of an anterograde RABV ∆G variant for novel neuroanatomical approaches invol...

    Matthias Georg Haberl, Silvia Viana da Silva in Brain Structure and Function (2015)