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Article
Neuroactive Steroids and Sex-Dimorphic Nervous Damage Induced by Diabetes Mellitus
Diabetes mellitus is a metabolic disease where improper glycaemic control may induce severe complications in different organs. In this review, we will discuss alterations occurring in peripheral and central ne...
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Article
Post-finasteride syndrome and post-SSRI sexual dysfunction: two sides of the same coin?
Sexual dysfunction is a clinical condition due to different causes including the iatrogenic origin. For instance, it is well known that sexual dysfunction may occur in patients treated with antidepressants lik...
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Article
Open AccessAxonal transport in a peripheral diabetic neuropathy model: sex-dimorphic features
Disruption of axonal transport plays a pivotal role in diabetic neuropathy. A sex-dimorphism exists in the incidence and symptomatology of diabetic neuropathy; however, no studies so far have addressed sex dif...
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Article
Open AccessThe lipogenic regulator Sterol Regulatory Element Binding Factor-1c is required to maintain peripheral nerve structure and function
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Article
Multimodal Analysis in Acute and Chronic Experimental Autoimmune Encephalomyelitis
Different experimental autoimmune encephalomyelitis models (EAE) have been developed. However, due to the different experimental conditions applied, observations simultaneously considering different pathologic...
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Article
Open AccessGender effect on neurodegeneration and myelin markers in an animal model for multiple sclerosis
Multiple sclerosis (MS) varies considerably in its incidence and progression in females and males. In spite of clinical evidence, relatively few studies have explored molecular mechanisms possibly involved in ...
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Article
Dihydroprogesterone Increases the Gene Expression of Myelin Basic Protein in Spinal Cord of Diabetic Rats
Alterations in myelin membranes, as well as in the expression of myelin proteins have been reported in experimental models of diabetes. Data here reported show for the first time that the mRNA levels of two is...