6 Result(s)

Article

Role of intravenous ketamine in the pathogenesis of secondary sclerosing cholangitis in critically ill patients: perpetrator or innocent bystander? Answers provided by forensic toxicology

Silke Leonhardt, Sven Baumann, Christian Jürgensen, Lars Hüter… in Intensive Care Medicine (2023)

Article

Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients

Increasing evidence suggests that secondary sclerosing cholangitis (SSC), which can lead to cirrhosis or liver failure, may be a hepatobiliary long-term complication of COVID-19. The aim of this study was to e...

Silke Leonhardt, Christian Jürgensen, Josephine Frohme… in Hepatology International (2023)

Article

Immunosuppressive effects of circulating bile acids in human endotoxemia and septic shock: patients with liver failure are at risk

Sepsis-induced immunosuppression is a frequent cause of opportunistic infections and death in critically ill patients. A better understanding of the underlying mechanisms is needed to develop targeted therapie...

Julia Leonhardt, Mirrin J. Dorresteijn, Sophie Neugebauer, Diana Mihaylov… in Critical Care (2023)

Article

PuraStat in gastrointestinal bleeding: results of a prospective multicentre observational pilot study

A recently developed haemostatic peptide gel for endoscopic application has been introduced to improve the management of gastrointestinal bleeding. The aim of this pilot study was to evaluate the feasibility, ...

Federica Branchi, Rolf Klingenberg-Noftz, Kristina Friedrich… in Surgical Endoscopy (2022)

Article

Trigger mechanisms of secondary sclerosing cholangitis in critically ill patients

In recent years the development of secondary sclerosing cholangitis in critically ill patients (SSC-CIP) has increasingly been perceived as a separate disease entity. About possible trigger mechanisms of SSC-C...

Silke Leonhardt, Wilfried Veltzke-Schlieker, Andreas Adler, Eckart Schott… in Critical Care (2015)