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APOE3ch alleviates Aβ and tau pathology and neurodegeneration in the human APPNL-G-F cerebral organoid model of Alzheimer’s disease
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Open AccessDigital transformation and firm performance: a case study on China’s listed companies in 2009–2020
Based on a panel fixed effect model, our paper explores the impact of digital transformation on the operation efficiency of Chinese A-share listed enterprises during 2009–2020. It conducts related robustness t...
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Allergic and Atopic Disease of the Pediatric Eye
Allergic and atopic diseases of the eye are extremely common conditions that can be challenging to both diagnose and treat. To help guide pediatric healthcare professionals, this review addresses the pathogene...
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A Rare Case of MDA-5-Positive Amyopathic Dermatomyositis with Rapidly Progressive Interstitial Lung Disease Following COVID-19 mRNA Vaccination — a Case Report
We report a rare case of new-onset MDA-5-positive amyopathic dermatomyositis with rapidly progressive interstitial lung disease (RP-ILD) following the second dose of the COVID-19 mRNA vaccine. Our patient was ...
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Open AccessAnti-angiogenesis and anti-metastasis effects of Polyphyllin VII on Hepatocellular carcinoma cells in vitro and in vivo
Polyphyllin VII (PP7), a steroidal saponin from P. polyphylla has been found to exert strong anticancer activity. Little is known about the anti-angiogenesis and anti-metastasis properties of PP7. In this study, ...
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Open AccessSystemic lupus Erythematosus activity and Hydroxychloroquine use before and after end-stage renal disease
SLE manifestations after ESRD may be underdiagnosed and undertreated, contributing to increased morbidity and mortality. Whether specific symptoms persist after ESRD or a shift towards new manifestations occur...
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Anti-liver cancer effect and the mechanism of arsenic sulfide in vitro and in vivo
This study aimed at investigating the anti-tumor effect of arsenic sulfide (As2S2) against liver cancer both in vivo and in vitro and to elucidate its underlying mechanisms.
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Blood-compatible Polyaniline Coated Electrospun Polyurethane Fiber Scaffolds for Enhanced Adhesion and Proliferation of Human Umbilical Vein Endothelial Cells
The endothelialization and anti-thrombotic abilities of tissue engineered vascular scaffolds are considered to be effective properties for improving the performance small-caliber vascular scaffolds. For this p...
