5 Result(s)

Article

Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8⁺ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer

A large proportion of the patients with cancer do not respond to immunotherapies. Recent studies suggested an important role for tumor-infiltrating cytotoxic T lymphocytes (CTL) in enhancing response to immuno...

Peisi Li, Dawang Zhou, Dongwen Chen, Yikan Cheng… in Journal of Biomedical Science (2023)

Article

Author Correction: Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression

Qiang Zhang, **aoya Yang, **jie Wu, Shubiao Ye, Junli Gong… in Cell Discovery (2023)

Article

Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression

Metabolic reprogramming is a hallmark of cancer. However, it is not well known how metabolism affects cancer progression. We identified that metabolic enzyme acyl-CoA oxidase 1 (ACOX1) suppresses colorectal ca...

Qiang Zhang, **aoya Yang, **jie Wu, Shubiao Ye, Junli Gong… in Cell Discovery (2023)

Article

NPM1 upregulates the transcription of PD-L1 and suppresses T cell activity in triple-negative breast cancer

Programmed cell death protein-1 (PD-1)/programmed cell death ligand-1 (PD-L1) interaction plays a crucial role in tumor-associated immune escape. Here, we verify that triple-negative breast cancer (TNBC) has h...

Ge Qin, **n Wang, Shubiao Ye, Yizhuo Li, Miao Chen, Shusen Wang… in Nature Communications (2020)