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Article
Open AccessApplication of the “Plan-Do-Check-Action” plan in improving the pass rate of the “National Medical Licensing Examination”
The National Medical Licensing Examination (NMLE) is the only objective, standardized metric to evaluate whether a medical student possessing the professional knowledge and skills necessary to work as a physic...
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Article
Open AccessThe impact of maternal intrahepatic cholestasis during pregnancy on the growth trajectory of offspring: a population-based nested case‒control cohort study
Intrahepatic cholestasis of pregnancy (ICP) is associated with an increased risk of adverse fetal outcomes, yet its influence on offspring growth remains unclear. Our study dynamically tracks growth rates in c...
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Article
Open AccessIdentification and validation of a prognostic signature based on six immune-related genes for colorectal cancer
Colorectal cancer (CRC) is a prevalent malignancy with high mortality and morbidity rates. Although the significant efficacy of immunotherapy is well established, it is only beneficial for a limited number of ...
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Article
Effects of Aromatherapy on Physical and Mental Health of Cancer Patients Undergoing Radiotherapy and/or Chemotherapy: A Meta-Analysis
Currently, aromatherapy is being increasingly utilized in clinical practice, particularly in managing the side effects associated with radiotherapy and chemoradiotherapy. However, it remains to be established ...
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Article
Minimum quantity lubrication machining nickel base alloy: a comprehensive review
Nickel-based alloys have great application value in aerospace, biomedical industry, chemical industry, and other fields. However, nickel-based alloys are known to be difficult to process, which will generate a...
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Article
Open AccessInterpretable machine learning model for early prediction of 28-day mortality in ICU patients with sepsis-induced coagulopathy: development and validation
Sepsis-induced coagulopathy (SIC) is extremely common in individuals with sepsis, significantly associated with poor outcomes. This study attempted to develop an interpretable and generalizable machine learnin...
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Article
Open AccessDeep learning and transfer learning identify breast cancer survival subtypes from single-cell imaging data
Single-cell multiplex imaging data have provided new insights into disease subtypes and prognoses recently. However, quantitative models that explicitly capture single-cell resolution cell-cell interaction fea...
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Article
Effect of internal and external chaotic stimuli on synchronization of piezoelectric auditory neurons in coupled time-delay systems
Hearing impairment is considered to be related to the damage of hair cells or synaptic terminals, which will cause varying degrees of hearing loss. Numerous studies have shown that cochlear implants can balanc...
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Article
Evaluation of nausea and vomiting in the first trimester on the risk of adverse birth outcomes and the contribution of genetic polymorphisms: a pilot prospective study
To evaluate the impact of Nausea and Vomiting in Pregnancy (NVP) on the risk of Preterm Birth (PTB) and Low Birth Weight (LBW), and explore the effect of genetic polymorphisms on the severity of NVP.
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Article
Open AccessA MRI-based radiomics model for predicting the response to anlotinb combined with temozolomide in recurrent malignant glioma patients
Anlotinib is a multitarget anti-angiogenic drug that combined with temozolomide (TMZ) can effectively prolongs the overall survival (OS) of recurrent malignant glioma(rMG),but some patients do not respond to a...
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Article
Open AccessTowards precision medicine based on a continuous deep learning optimization and ensemble approach
We developed a continuous learning system (CLS) based on deep learning and optimization and ensemble approach, and conducted a retrospective data simulated prospective study using ultrasound images of breast m...
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Article
Timing of Sexuality Education: Hong Kong Preteens’ Perception of Sexual Health
Although young people want to know more about sexuality, they do not feel they have received what they need to learn. In Chinese societies, scant research has solicited direct input from the youth to obtain th...
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Article
Prognostic value of a microRNA-pair signature in laryngeal squamous cell carcinoma patients
Predicting the prognosis in laryngeal squamous cell carcinoma (LSCC) patients will improve clinical decision-making. Here, we aimed to identify a qualitative signature based on the within-sample relative expre...
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Article
Lipid metabolism-related genes as biomarkers and therapeutic targets reveal endometrial receptivity and immune microenvironment in women with reproductive dysfunction
In recent years, alterations in lipid metabolism are currently considered a hallmark feature of many diseases. However, the role in women with reproductive dysfunction (WRD) remains to be fully elucidated. Her...
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Article
An InSAR and depth-integrated coupled model for potential landslide hazard assessment
Assessing the hazard of potential landslides is crucial for develo** mitigation strategies for landslide disasters. However, accurate assessment of landslide hazard is limited by the lack of landslide invent...
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Article
The controlled synthesis of porous silver structure on carbon fibres and their sterilization performance
Ag@C fibres with porous silver structure were synthesized with a surface-hydrolyzed polyacrylonitrile (PAN) fibre as a template and by a hydrazine hydrate reduction and carbonization process. The composition a...
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Article
Sex Education Programs for Preteens: A Review of Relevant Outcome Studies in Nine Countries
Most sex education programs (SEPs) are designed for children in middle and high schools. This study aimed to analyze sex education curricula with a mission to educate pre-pubertal children. A systematic review...
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Article
Open AccessEvaluation of optical quality in pterygium patients with a new modified sutureless and glue-free method
Modified sutureless and glue-free method is an effective and novel surgical approach for pterygium. We aim to evaluate optical quality in pterygium treated with the new method and investigate the clinical appl...
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Article
Fabrication of g-C3N4@NiFe-LDH heterostructured nanocomposites for highly efficient photocatalytic removal of rhodamine B
This study reports that the novel binary g-C3N4@NiFe-LDH heterostructured photocatalysts were simply prepared by loading well-dispersed g-C3N4 nanosheets on the surface of NiFe-LDH precursor via the hydrothermal ...
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Article
Solution structure of the voltage-gated Tim23 channel in complex with a mitochondrial presequence peptide
