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Next-generation molecular diagnosis: single-cell sequencing from bench to bedside

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  1. Article

    Open Access

    Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization

    Human intestinal peptide transporter PEPT1 is commonly repressed in human colorectal cancer (CRC), yet its relationship with sensitivity to the common CRC treatment ubenimex has not previously been elucidated....

    Yanhong Wang, Jiaqi Wang, Lingrong Yang, Liqing Qiu, Yuhui Hua… in Cell Death & Disease (2021)

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  2. Article

    Open Access

    CAF-secreted CXCL1 conferred radioresistance by regulating DNA damage response in a ROS-dependent manner in esophageal squamous cell carcinoma

    Five-year survival rate of esophageal squamous cell carcinoma (ESCC) patients treated with radiotherapy is <20%. Our study aimed to investigate whether cancer-associated fibroblasts (CAFs), one major component...

    Hongfang Zhang, **g Yue, Zhenzhen Jiang, Rong**g Zhou, … in Cell Death & Disease (2017)

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