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Chapter and Conference Paper
Overlap** Community Discovery Algorithm Based on Three-Level Neighbor Node Influence
In view of the high time complexity of the current overlap** community discovery algorithm and the low stability, an overlap** community discovery algorithm OCDITN based on three-level neighbor influence i...
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Article
Open AccessSHANK2 is a frequently amplified oncogene with evolutionarily conserved roles in regulating Hippo signaling
Dysfunction of the Hippo pathway enables cells to evade contact inhibition and provides advantages for cancerous overgrowth. However, for a significant portion of human cancer, how Hippo signaling is perturbed...
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Article
Open AccessDefining relative mutational difficulty to understand cancer formation
Most mutations in human cancer are low-frequency missense mutations, whose functional status remains hard to predict. Here, we show that depending on the type of nucleotide change and the surrounding sequences...
