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  1. Article

    Open Access

    The effect of specimen processing time on HER2 expression in gastric cancer and esophagogastric junction cancer: a single-center retrospective observational study

    Recent developments in the field of companion diagnosis and molecular-targeting therapeutic agents have helped in develo** treatments targeting human epidermal growth factor receptor 2 (HER2) in gastric canc...

    Yoshitomo Yanagimoto, Hiroshi Imamura, Shiro Adachi, Kazuki Odagiri in BMC Cancer (2023)

  2. No Access

    Article

    Nivolumab dose escalation triggered immune checkpoint inhibitor-induced colitis after 147 weeks of prolonged stable use in a patient with lung cancer: a case report

    A 56-year-old man with advanced lung adenocarcinoma presented to the emergency department with a 6-day history of diarrhea. He was treated for lung cancer with nivolumab 3 mg/kg (144 mg/body) every 2 weeks (Q2...

    Kazumasa Soma, Tsutomu Nishida, Naoto Osugi in Clinical Journal of Gastroenterology (2022)

  3. No Access

    Article

    Resection of a large gastrointestinal stromal tumor in the stomach after imatinib treatment in a 90-year-old patient

    A 90-year-old woman presented with a 1-month history of progressive abdominal fullness. Contrast computed tomography (CT) showed a large 17-cm mass located adjacent to the antrum of the stomach without metasta...

    Aya Sugimoto, Tsutomu Nishida, Masashi Hirota in Clinical Journal of Gastroenterology (2021)

  4. No Access

    Article

    Automatic Remasking of Digital Subtraction Angiography Images in Pulmonary Angiography

    In pulmonary angiography, the heartbeat creates artifacts that hinder extraction of blood vessel images in digital subtraction angiography. Remasking according to the cardiac phase of the angiogram may be effe...

    Takashi Mizukuchi, Takeshi Uemura, Satoru Kondo, Shinji Abe in Journal of Digital Imaging (2020)

  5. Article

    Open Access

    Medium-term health-related quality of life in patients with pulmonary arterial hypertension treated with goal-oriented sequential combination therapy based on exercise capacity

    Pulmonary arterial hypertension (PAH) remains a life-threatening condition, despite modern therapies. We prospectively investigated the therapeutic health-related quality of life (HRQOL) effects of goal-orient...

    Akihiro Hirashiki, Shiro Adachi, Naoki Okumura in Health and Quality of Life Outcomes (2019)

  6. Article

    Open Access

    Usefulness of scoring right ventricular function for assessment of prognostic factors in patients with chronic thromboembolic pulmonary hypertension

    Right ventricular (RV) function is associated with prognosis in chronic thromboembolic pulmonary hypertension (CTEPH). This study aimed to establish an RV dysfunction score using RV echocardiographic parameter...

    Yoshihiro Kamimura, Naoki Okumura, Shiro Adachi, Shigetake Shimokata in Heart and Vessels (2018)

  7. Article

    Open Access

    Extracranial meningiomas concurrently found in the lung and vertebral bone: a case report

    Primary pulmonary meningiomas are very rare, and primary intraosseous meningiomas outside the head and neck region have not yet been reported. We report an extremely unusual case of concurrent meningiomas aris...

    Hiromi Tamura, Yasushi Otani, Takashi Iwazawa in Journal of Medical Case Reports (2018)

  8. Article

    Open Access

    A case of intraductal papillary-mucinous neoplasm of the pancreas penetrating into the stomach and spleen successfully treated by total pancreatectomy

    Intraductal papillary-mucinous neoplasms (IPMNs) are potentially malignant intraductal epithelial neoplasms that sometimes penetrate into other organs. To the best of our knowledge, no report has yet described...

    Takashi Harino, Yoshito Tomimaru, Kozo Noguchi, Hirotsugu Nagase in Surgical Case Reports (2018)

  9. Article

    Open Access

    Left ventricular end-diastolic dimension and septal e′ are predictors of cardiac index at rest, while tricuspid annular plane systolic excursion is a predictor of peak oxygen uptake in patients with pulmonary hypertension

    Little is known regarding a correlation of hemodynamics at rest or exercise capacity with echocardiographic parameters in patients with pulmonary hypertension (PH). To clarify these potential correlations, we ...

    Yoshihisa Nakano, Naoki Okumura, Shiro Adachi, Shigetake Shimokata in Heart and Vessels (2018)

  10. Article

    Open Access

    Mesonephric adenocarcinoma of the uterine corpus with intracystic growth completely confined to the myometrium: a case report and literature review

    Mesonephric adenocarcinoma (MA) is a rare tumor believed to arise from mesonephric remnants occurring mostly in the uterine cervix and, to a lesser extent, the corpus. Since the first case report of MA in the ...

    Hiroka Ando, Yuko Watanabe, Minori Ogawa, Hiromi Tamura in Diagnostic Pathology (2017)

  11. No Access

    Article

    Effect of particle size and shape on nonresonant random laser action of dye-doped polymer random media

    We present an experimental study of the light emission from dye-doped polymer random media dispersed with TiO2 particles of various sizes, shapes, and structures. Random lasing with nonresonant feedback, similar ...

    Takashi Okamoto, Shiro Adachi in Optical Review (2010)

  12. No Access

    Article

    A case of metastatic lobular breast carcinoma with detection of the primary tumor after ten years

    Lobular carcinoma of the breast is known to metastasize to unusual sites such as the gastrointestinal tract, peritoneum, and gynecologic organs.

    Tetsuro Kobayashi, Shiro Adachi, Yasuki Matsuda, Syusei Tominaga in Breast Cancer (2007)

  13. No Access

    Article

    A case of invasive lobular carcinoma of the breast first manifesting with duodenal obstruction

    Lobular carcinoma of the breast presents with various clinical manifestations. Lobular carcinoma comprises about one fifth of cases of ductal carcinoma. Intestinal metastasis is dominant in cases of lobular ca...

    Tetsuro Kobayashi, Kunitaka Shibata, Yasuki Matsuda, Shusei Tominaga in Breast Cancer (2004)