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  1. No Access

    Article

    Predictors of dropout in university students participating in an 8-week e-mail-based cognitive-behavioral therapy for insomnia intervention

    We conducted an exploratory study to identify risk factors of dropout in an 8-week e-mail-based cognitive-behavioral therapy for insomnia (REFRESH) to improve sleep among university students with insomnia symp...

    Hyo** Nam, **young Chang, Mickey Trockel, Isa Okajima… in Sleep and Breathing (2023)

  2. Article

    Open Access

    A Novel Class of HIV-1 Antiviral Agents Targeting HIV via a SUMOylation-Dependent Mechanism

    We have recently identified a chemotype of small ubiquitin-like modifier (SUMO)-specific protease (SENP) inhibitors. Prior to the discovery of their SENP inhibitory activity, these compounds were found to inhi...

    Ikenna G. Madu, Shirley Li, Baozong Li, Haitang Li, Tammy Chang… in Scientific Reports (2015)

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  3. No Access

    Article

    Biosensor-based small molecule fragment screening with biolayer interferometry

    Biosensor-based fragment screening is a valuable tool in the drug discovery process. This method is advantageous over many biochemical methods because primary hits can be distinguished from non-specific or non...

    Charles A. Wartchow, Frank Podlaski… in Journal of Computer-Aided Molecular Design (2011)

  4. No Access

    Article

    Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domains

    The three-dimensional structure of the ligand-binding region of human E-selectin has been determined at 2.0 Å resolution. The structure reveals limited contact between the two domains and a coordination of Ca2+ n...

    Bradford J. Graves, Robert L. Crowther, Chitra Chandran, John M. Rumberger… in Nature (1994)