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  1. No Access

    Article

    Comparative efficacy and safety of combination therapy with infliximab for Crohn’s disease: a systematic review and network meta-analysis

    There is not enough information to position medications for the treatment of Crohn’s disease (CD). Therefore, using a network meta-analysis and systematic review, we evaluated the efficacy and safety of combin...

    Bing Han, Daiyuan Tang, in International Journal of Colorectal Disease (2023)

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    Article

    Force model of freeform surface multi-axis machining with fillet end mill based on analytical contact analysis

    In the multi-axis machining of freeform surface, compared with ball end mill, the fillet end mill has higher machining efficiency under the same residual height and has been widely used. As the most important ...

    Minglong Guo, Zhaocheng Wei, Shiquan Li in The International Journal of Advanced Manu… (2022)

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    Article

    LncRNA HLA-F-AS1 promotes colorectal cancer metastasis by inducing PFN1 in colorectal cancer-derived extracellular vesicles and mediating macrophage polarization

    Colorectal cancer (CRC) is a prevalent malignancy with high incidence and low 5-year survival. Long non-coding RNAs (lncRNAs), a kind of specific RNA transcript, are increasingly implicated in tumor growth, me...

    **g Zhang, Shiquan Li, **aona Zhang, Chao Li, Jiantao Zhang in Cancer Gene Therapy (2021)

  4. Article

    Open Access

    Extracellular vesicles-derived microRNA-222 promotes immune escape via interacting with ATF3 to regulate AKT1 transcription in colorectal cancer

    Immunotherapy has been recently established as a new direction for the treatment of colorectal cancer (CRC), a gastrointestinal cancer. In this investigation, we aimed to expound how the posttranscriptional re...

    Shiquan Li, Guoqiang Yan, Meng Yue, Lei Wang in BMC Cancer (2021)

  5. No Access

    Article

    Modal parameter identification of general cutter based on milling stability theory

    In the field of CNC milling, chatter has been a hot research topic, which is related to machining quality, precision and cost. Stability lobe diagram (SLD) reflects the vibration of the machining system under ...

    Minglong Guo, Zhaocheng Wei, Minjie Wang in Journal of Intelligent Manufacturing (2021)

  6. No Access

    Article

    Mechanical modeling of five-axis single root clean-up machining of complex surface

    Root clean-up machining is an important process for five-axis machining of complex curved surface parts. Subjected to harsh cutting conditions and lack of analysis of cutting force, single root clean-up machin...

    Minglong Guo, Zhaocheng Wei, Minjie Wang in The International Journal of Advanced Manu… (2019)

  7. No Access

    Article

    An identification model of cutting force coefficients for five-axis ball-end milling

    Five-axis ball-end milling is widely used in energy, ship, aerospace, and other fields. As one of the difficulties in milling research, milling force is often critical to the processing efficiency and quality ...

    Minglong Guo, Zhaocheng Wei, Minjie Wang in The International Journal of Advanced Manu… (2018)