16 Result(s)

Article

Despite low viral titer in saliva samples, Sanger-based SARS-CoV-2 spike gene sequencing is highly applicable for the variant identification

This study aimed to compare the performance of Sanger-based SARS-CoV-2 spike gene sequencing and Next Generation Sequencing (NGS)-based full-genome sequencing for variant identification in saliva samples with ...

Ko Ko, Kazuaki Takahashi, Noriaki Ito, Aya Sugiyama… in BMC Medical Genomics (2023)

Article

Residual risk of mother-to-child transmission of HBV despite timely Hepatitis B vaccination: a major challenge to eliminate hepatitis B infection in Cambodia

In countries with intermediate or high hepatitis B virus (HBV) endemicity, mother-to-child transmission (MTCT) represents the main route of chronic HBV infection. There is a paucity of information on HBV MTCT ...

Bunthen E, Ko Ko, Rattana Kim, Shintaro Nagashima, Serge Ouoba… in BMC Infectious Diseases (2023)

Article

Intermediate hepatitis B virus infection prevalence among 1622 pregnant women in rural Burkina Faso and implications for mother-to-child transmission

In highly endemic countries for hepatitis B virus (HBV) infection, childhood infection, including mother-to-child transmission (MTCT), represents the primary transmission route. High maternal DNA level (viral ...

Serge Ouoba, Ko Ko, Moussa Lingani, Shintaro Nagashima… in Scientific Reports (2023)

Article

Author Correction: Seroepidemiological study of factors affecting anti-spike IgG antibody titers after a two-dose mRNA COVID-19 vaccination in 3744 healthy Japanese volunteers

Aya Sugiyama, Akemi Kurisu, Shintaro Nagashima, Kiyomi Hando… in Scientific Reports (2023)

Article

Neutralizing Type I Interferon Autoantibodies in Japanese Patients with Severe COVID-19

Autoantibodies (aAbs) to type I interferons (IFNs) have been found in less than 1% of individuals under the age of 60 in the general population, with the prevalence increasing among those over 65. Neutralizing...

Shohei Eto, Yoko Nukui, Miyuki Tsumura, Yu Nakagama… in Journal of Clinical Immunology (2022)

Article

Seroepidemiological study of factors affecting anti-spike IgG antibody titers after a two-dose mRNA COVID-19 vaccination in 3744 healthy Japanese volunteers

Several factors related to anti-spike(S) IgG antibody titers after mRNA COVID-19 vaccination have been elucidated, but the magnitude of the effects of each factor has not been fully understood. This cross-sect...

Aya Sugiyama, Akemi Kurisu, Shintaro Nagashima, Kiyomi Hando… in Scientific Reports (2022)

Article

Prevalence and genotype distribution of viral hepatitis B in Cambodia between 1990 and 2020: a systematic review and meta-analysis

Hepatitis B virus (HBV) infection is one of the major public health problems globally as well as in Cambodia. Continuous information on HBV infection burden is required to implement effective disease control s...

Bunthen E, Pichetra Ou, Serge Ouoba, Md Razeen Ashraf Hussain… in Archives of Public Health (2022)

Article

Mass Screening of SARS-CoV-2 Variants using Sanger Sequencing Strategy in Hiroshima, Japan

This study aimed to develop the feasible and effective universal screening strategy of the notable SARS-CoV-2 variants by Sanger Sequencing Strategy and then practically applied it for mass screening in Hirosh...

Ko Ko, Kazuaki Takahashi, Shintaro Nagashima, Bunthen E, Serge Ouoba… in Scientific Reports (2022)

Article

Epidemiologic profile of hepatitis C virus infection and genotype distribution in Burkina Faso: a systematic review with meta-analysis

Detailed characteristics of Hepatitis C virus (HCV) infection in Burkina Faso are scarce. The main aim of this study was to assess HCV seroprevalence in various settings and populations at risk in Burkina Faso...

Serge Ouoba, Jean Claude Romaric **dwinde Ouedraogo… in BMC Infectious Diseases (2021)

Article

Prevalence of total hepatitis A antibody among 5 to 7 years old children and their mothers in Cambodia

This study determined the prevalence of total hepatitis A antibody (anti-HAV) among 5–7 years old children and their mothers in the whole Cambodia, using a nationwide study, and examined the differences betwee...

Shintaro Nagashima, Ko Ko, Chikako Yamamoto, E. Bunthen, Serge Ouoba… in Scientific Reports (2021)

Article

Existence of hepatitis B virus surface protein mutations and other variants: demand for hepatitis B infection control in Cambodia

This study aimed to detect Hepatitis B virus (HBV) genome sequences and their variants as of nationwide scale using dried blood spot (DBS) samples and to provide up-to-date reference data for infection control...

Ko Ko, Kazuaki Takahashi, Shintaro Nagashima, Chikako Yamamoto… in BMC Infectious Diseases (2020)

Article

Evaluation of the efficiency of dried blood spot-based measurement of hepatitis B and hepatitis C virus seromarkers

Although hepatitis B (HBV) and C (HCV) virus infections are still global health issues, measuring sero-markers by standard venipuncture is challenging in areas limited with the adequate human resources and bas...

Chikako Yamamoto, Shintaro Nagashima, Mitsuo Isomura, Ko Ko… in Scientific Reports (2020)

Article

The changing epidemiology of hepatitis B and C infections in Nanoro, rural Burkina Faso: a random sampling survey

This study sought to provide up-to-date hepatitis B (HBV) and C (HCV) seroprevalence in rural Burkina Faso decade after hepatitis B vaccine was introduced in the national immunization scheduled for children.

Moussa Lingani, Tomoyuki Akita, Serge Ouoba, Shintaro Nagashima… in BMC Infectious Diseases (2020)

Article

High possibility of hepatocarcinogenesis in HBV genotype C1 infected Cambodians is indicated by 340 HBV C1 full-genomes analysis from GenBank

Approximately 75% of hepatocellular carcinomas (HCC) occur in Asia; core promoter mutations are associated with HCC in HBV genotype C, the dominant genotype in Cambodia. We analyzed these mutations in Cambodia...

Channarena Chuon, Kazuaki Takahashi, Junko Matsuo, Keiko Katayama… in Scientific Reports (2019)

Article

Very low prevalence of anti-HAV in Japan: high potential for future outbreak

Since the early 21^st century, almost all developed countries have had a very low hepatitis A virus antibody (anti-HAV) sero-prevalence profile, as sanitation conditions and health care facilities have been optimi...

Chikako Yamamoto, Ko Ko, Shintaro Nagashima, Takayuki Harakawa… in Scientific Reports (2019)