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  1. No Access

    Article

    Antiestrogenic effect of paradichlorobenzene in immature mice and rats

    A significant increase/decrease in uterine and ovarian weights was occasionally seen in immature mice and rats subcutaneously administered paradichlorobenzene (PDCB) at doses of 22–67 mg/kg/day, but the result...

    Osamu Takahashi, Shinshi Oishi, Masako Yoneyama, Akio Ogata… in Archives of Toxicology (2007)

  2. No Access

    Article

    Male reproductive toxicity of four bisphenol antioxidants in mice and rats and their estrogenic effect

    Male mice and rats were fed a diet containing four bisphenol antioxidants, 2,2′-methylenebis(4-ethyl-6-tert-butylphenol) (ME), 2,2′-methylenebis(4-methyl-6-tert-butylphenol) (MM), 4,4′-butylidenebis(3-methyl-6-te...

    Osamu Takahashi, Shinshi Oishi in Archives of Toxicology (2006)

  3. No Access

    Article

    Effects of butyl paraben on the male reproductive system in mice

    Parabens are alkyl ester compounds of p-hydroxybenzoic acid widely used as preservatives in foodstuffs, cosmetics, toiletries and pharmaceuticals. These compounds are known to exert a weak estrogenic activity in...

    Shinshi Oishi in Archives of Toxicology (2002)

  4. No Access

    Article

    Effects of ingestion of cadmium-polluted rice or low-dose cadmium-supplemented diet on the endogenous metal balance in female rats

    The concentrations of endogenous metal ions in liver, kidney, and bone tissues of female rats were measured after ingestion of cadmium-polluted rice (1.24 ppm as Cd) or cadmium-supplemented rice (1.24 and 4.96...

    Shinshi Oishi, Jun-ichi Nakagawa, Masanori Ando in Biological Trace Element Research (2001)

  5. No Access

    Article

    Testicular toxicity of dietary 2,2-bis(4-hydroxyphenyl)propane (bisphenol A) in F344 rats

    Male F344/DuCrj (Fischer) rats were given bisphenol A (BPA) in the diet at levels of 0 (control), 0.25, 0.50 and 1.00%, equivalent to 0, 235, 466 and 950 mg/kg per day, respectively, for 44 days. Body weight ...

    Osamu Takahashi, Shinshi Oishi in Archives of Toxicology (2001)

  6. No Access

    Article

    Effects of phthalic acid esters on testicular mitochondrial functions in the rat

    Although it is well established that high dose administration of di(2-ethylhexyl) phthalate (DEHP) and its monoester metabolite (MEHP) induces severe testicular atrophy in rats, the mechanisms of this testicul...

    Shinshi Oishi in Archives of Toxicology (1990)

  7. No Access

    Article

    Effects of co-administration of Di(2-ethylhexyl)phthalate and testosterone on several parameters in the testis and pharmacokinetics of its mono-de-esterified metabolite

    The administration of 1 g/kg di(2-ethylhexyl) phthalate (DEHP) or 5 mg/kg testosterone for 1 week did not affect the testicular and prostatic gland weights in rats. However, co-administration of DEHP and testo...

    Shinshi Oishi in Archives of Toxicology (1989)

  8. No Access

    Article

    Mutagenicity of Tama River sediments

    Shinshi Oishi, Osamu Takahashi in Bulletin of Environmental Contamination and Toxicology (1987)

  9. No Access

    Article

    Testicular atrophy induced by di(2-ethylhexyl)phthalate: changes in histology, cell specific enzyme activities and zinc concentrations in rat testis

    Daily administration of 2 g/kg/day di(2-ethyl-hexyl)phthalate (DEHP) to immature rats was found to cause testicular atrophy and reduce zinc concentration. Specific activities of testicular enzymes associated w...

    Shinshi Oishi in Archives of Toxicology (1986)

  10. No Access

    Article

    Distribution and elimination of di-2-ethylhexyl phthalate (DEHP) and mono-2-ethylhexyl phthalate (MEHP) after a single oral administration of DEHP in rats

    The distribution and elimination of di-2-ethylhexyl phthalate (DEHP) and mono-2-ethylhexyl phthalate (MEHP) after a single oral administration of DEHP (25 mmol/kg) were studied. A gas-liquid Chromatographic me...

    Shinshi Oishi, Kogo Hiraga in Archives of Toxicology (1982)

  11. No Access

    Article

    Effect of phthalic acid esters on gonadal function in male rats

    Shinshi Oishi, Kogo Hiraga in Bulletin of Environmental Contamination and Toxicology (1979)

  12. No Access

    Article

    Influence of polychlorinated dibenzofurans (PCDFs) and polychlorinated biphenyls (PCBs) to serum protein components in rats

    Shinshi Oishi in Bulletin of Environmental Contamination and Toxicology (1977)