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Article
Open AccessIncreased epithelial stem cell traits in advanced endometrial endometrioid carcinoma
It has been recognized cancer cells acquire characters reminiscent of those of normal stem cells, and the degree of stem cell gene expression correlates with patient prognosis. Lgr5(+) or CD133(+) epithelial s...
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Article
Open AccessMicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells
Mesenchymal stem cell (MSC) found in bone marrow (BM-MSCs) and the Wharton's jelly matrix of human umbilical cord (WJ-MSCs) are able to transdifferentiate into neuronal lineage cells both in vitro and in vivo and...
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Article
Open AccessGenetic module and miRNome trait analyses reflect the distinct biological features of endothelial progenitor cells from different anatomic locations
Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair, yet EPCs from different anatomic locations possess unique biological properties. The underlying mechanisms are unclear.
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Article
Open AccessDistinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses
Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair. Currently EPCs are defined as either early and late EPCs based on their biological properties and their time of appear...
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Article
Open AccessmiRNome traits analysis on endothelial lineage cells discloses biomarker potential circulating microRNAs which affect progenitor activities
Endothelial progenitor cells (EPCs) play a fundamental role in not only blood vessel development but also post-natal vascular repair. Currently EPCs are defined as early and late EPCs based on their biological...
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Article
Open AccessDiscovering monotonic stemness marker genes from time-series stem cell microarray data
Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Mon...
