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    Article

    Fecal Protein Analysis of Dusp6 Knockout C57BL/6J Mice by Metaproteomics

    The research of obesity and gut microbiota has been carried out for years, yet the study process was in a slow pace for several challenges to conquer. As a complex status of disorder, the contributing factors ...

    Mei-Chi Lin, Zi-Yun Peng, Hsiu-Chuan Chou in Applied Biochemistry and Biotechnology (2023)

  2. Article

    Open Access

    Discovering monotonic stemness marker genes from time-series stem cell microarray data

    Identification of genes with ascending or descending monotonic expression patterns over time or stages of stem cells is an important issue in time-series microarray data analysis. We propose a method named Mon...

    Hsei-Wei Wang, Hsing-Jen Sun, Ting-Yu Chang, Hung-Hao Lo, Wei-Chung Cheng in BMC Genomics (2015)

  3. Article

    Open Access

    miRNome traits analysis on endothelial lineage cells discloses biomarker potential circulating microRNAs which affect progenitor activities

    Endothelial progenitor cells (EPCs) play a fundamental role in not only blood vessel development but also post-natal vascular repair. Currently EPCs are defined as early and late EPCs based on their biological...

    Ting-Yu Chang, Tse-Shun Huang, Hsei-Wei Wang, Shing-Jyh Chang, Hung-Hao Lo in BMC Genomics (2014)

  4. Article

    Open Access

    Distinct angiogenesis roles and surface markers of early and late endothelial progenitor cells revealed by functional group analyses

    Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair. Currently EPCs are defined as either early and late EPCs based on their biological properties and their time of appear...

    Cheng-Chung Cheng, Shing-Jyh Chang, Yu-Neng Chueh, Tse-Shun Huang in BMC Genomics (2013)

  5. Article

    Open Access

    Genetic module and miRNome trait analyses reflect the distinct biological features of endothelial progenitor cells from different anatomic locations

    Endothelial progenitor cells (EPCs) play a fundamental role in post-natal vascular repair, yet EPCs from different anatomic locations possess unique biological properties. The underlying mechanisms are unclear.

    Cheng-Chung Cheng, Hung-Hao Lo, Tse-Shun Huang, Yi-Chieh Cheng in BMC Genomics (2012)

  6. Article

    Open Access

    MicroRNA-34a modulates genes involved in cellular motility and oxidative phosphorylation in neural precursors derived from human umbilical cord mesenchymal stem cells

    Mesenchymal stem cell (MSC) found in bone marrow (BM-MSCs) and the Wharton's jelly matrix of human umbilical cord (WJ-MSCs) are able to transdifferentiate into neuronal lineage cells both in vitro and in vivo and...

    Shing-Jyh Chang, Shun-Long Weng, Jui-Yu Hsieh, Tao-Yeuan Wang in BMC Medical Genomics (2011)

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    Article

    Synchrotron microangiography studies of angiogenesis in mice with microemulsions and gold nanoparticles

    We present an effective solution for the problem of contrast enhancement in phase-contrast microangiography, with the specific objective of visualising small (<8 µm) vessels in tumor-related microangiogenesis....

    Chia-Chi Chien, C. H. Wang, C. L. Wang, E. R. Li in Analytical and Bioanalytical Chemistry (2010)

  8. Article

    Open Access

    Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma

    It has been recognized cancer cells acquire characters reminiscent of those of normal stem cells, and the degree of stem cell gene expression correlates with patient prognosis. Lgr5(+) or CD133(+) epithelial s...

    Shing-Jyh Chang, Tao-Yeuan Wang, Chan-Yen Tsai, Tzu-Fang Hu in BMC Genomics (2009)

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    Article

    Effects on Tyrosinase Activity by the Extracts of Ganoderma lucidum and Related Mushrooms

    The inhibitory effects on tyrosinase activity by extracts of several mushrooms belonging to Basidiomycetes were evaluated. Among the tested mushrooms (Ganoderma lucidum, Antrodia camphorat...

    Chih-Ching Chien, Mei-Ling Tsai, Chin-Chu Chen, Shing-Jyh Chang in Mycopathologia (2008)