-
Article
Open AccessZeb2 regulates differentiation of long-lived effector of invariant natural killer T cells
After activation, some invariant natural killer T (iNKT) cells are differentiated into Klrg1+ long-lived effector NKT1 cells. However, the regulation from the effector phase to the memory phase has not been eluci...
-
Article
Open AccessIdentification of TCR repertoires in functionally competent cytotoxic T cells cross-reactive to SARS-CoV-2
SARS-CoV-2-specific CD8+ T cells are scarce but detectable in unexposed healthy donors (UHDs). It remains unclear whether pre-existing human coronavirus (HCoV)-specific CD8+ T cells are converted to functionally ...
-
Article
Open AccessEomes transcription factor is required for the development and differentiation of invariant NKT cells
Eomes regulates the differentiation of CD8+ T cells into effector and memory phases. However, its role in invariant (i)NKT cells remains unknown. Here, we show the impact of Eomes on iNKT cells in the thymus and ...