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  1. Article

    Open Access

    CLEC5A mediates Zika virus-induced testicular damage

    Zika virus (ZIKV) infection is clinically known to induce testicular swelling, termed orchitis, and potentially impact male sterility, but the underlying mechanisms remain unclear. Previous reports suggested t...

    Hsin-Wei Wang, Hsing-Han Li, Shih-Cheng Wu in Journal of Biomedical Science (2023)

  2. Article

    Open Access

    Intestinal microbial dysbiosis aggravates the progression of Alzheimer’s disease in Drosophila

    Neuroinflammation caused by local deposits of Aβ42 in the brain is key for the pathogenesis and progression of Alzheimer’s disease. However, inflammation in the brain is not always a response to local primary ins...

    Shih-Cheng Wu, Zih-Syuan Cao, Kuo-Ming Chang, Jyh-Lyh Juang in Nature Communications (2017)

  3. No Access

    Article

    Overproduction of soluble recombinant transglutaminase from Streptomyces netropsis in Escherichia coli

    A novel microbial transglutaminase (TGase) from the cultural filtrate of Streptomyces netropsis BCRC 12429 (Sn) was purified. The specific activity of the purified TGase was 18.2 U/mg protein with an estimated mo...

    Yu-Jen Yu, Shih-Cheng Wu, Hung-Hsiang Chan in Applied Microbiology and Biotechnology (2008)