1,428 Result(s)
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Benefits of Hepatitis C Viral Eradication: A Real-World Nationwide Cohort Study in Taiwan
Chronic hepatitis C (CHC) increases the risk of liver cirrhosis (LC) and hepatocellular carcinoma (HCC). This nationwide cohort study assessed the effectiveness of viral eradication of CHC.
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The effect of calcium oxalate stones and uric acid stones on male sexual function
This study compared the effects of calcium oxalate stones and uric acid stones on male sexual function.
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Open AccessHeat-related illness and dementia: a study integrating epidemiological and experimental evidence
Heat-related illness (HRI) is commonly considered an acute condition, and its potential long-term consequences are not well understood. We conducted a population-based cohort study and an animal experiment to ...
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Impact of hepatic artery variation on surgical and oncological outcomes in robotic pancreaticoduodenectomy
In patients with hepatic artery variation (HAV), feasibility and justification of robotic pancreatoduodenectomy (RPD) for periampullary lesions have been not been well established.
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Open AccessExome sequencing and genome-wide association analyses unveils the genetic predisposition in hydroxychloroquine retinopathy
To unveil the candidate susceptibility genes in chloroquine/hydroxychloroquine (CQ/HCQ) retinopathy using whole exome sequencing (WES) and genome-wide association study (GWAS).
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Open AccessA Phase 3, Randomized, Controlled Trial Evaluating the Efficacy and Safety of Ropeginterferon Alfa-2b in Patients with Moderate COVID-19
Ropeginterferon alfa-2b is a novel mono-pegylated proline-interferon. This clinical study aimed to evaluate its antiviral efficacy of ropeginterferon alfa-2b against SARS-CoV-2 infection.
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Open AccessLikelihood-of-harm/help of microsurgery compared to radiosurgery in large vestibular schwannoma
It has been shown that in large vestibular schwannomas (VS), radiosurgery (SRS) is inferior with respect to tumor control compared to microsurgical resection (SURGERY). However, SURGERY poses a significantly high...
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Open AccessSub-seasonal prediction skill: is the mean state a good model evaluation metric?
Evaluating forecast models encompasses assessing their ability to accurately depict observed climate states and predict future climate variables. Various evaluation methods, from computationally efficient meas...
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Open AccessA time of emergence (TOE) analysis on the impact and uncertainty of global warming on Korean peak summers
In recent years, South Korea has experienced a notable escalation in the intensity and frequency of summer heat. To quantitatively gauge the impact of global warming on Korean summers, this study employs the T...
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Open AccessCystic vestibular schwannoma – a subgroup analysis from a comparative study between radiosurgery and microsurgery
Some vestibular schwannoma (VS) show cystic morphology. It is known that these cystic VS bear different risk profiles compared to solid VS in surgical treatment. Still, there has not been a direct comparative ...
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Health-related quality of life by veterans RAND 12 and healthcare resource utilization in cancer patients with sleep disorders: insights from the Medical Expenditure Panel Survey
This study aims to investigate the joint effects of cancer and sleep disorders on the health-related quality of life (HRQoL), healthcare resource utilization, and expenditures among US adults.
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Open AccessUse of phase plate cryo-EM reveals conformation diversity of therapeutic IgG with 50 kDa Fab fragment resolved below 6 Å
While cryogenic electron microscopy (cryo-EM) is fruitfully used for harvesting high-resolution structures of sizable macromolecules, its application to small or flexible proteins composed of small domains lik...
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Open AccessIntrinsically stretchable organic photovoltaics by redistributing strain to PEDOT:PSS with enhanced stretchability and interfacial adhesion
Intrinsically stretchable organic photovoltaics have emerged as a prominent candidate for the next-generation wearable power generators regarding their structural design flexibility, omnidirectional stretchabi...
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Open AccessPower-Doppler-based NH002 microbubble sonoporation with chemotherapy relieves hypoxia and enhances the efficacy of chemotherapy and immunotherapy for pancreatic tumors
Pancreatic ductal adenocarcinoma (PDAC) poses challenges due to late-stage diagnosis and limited treatment response, often attributed to the hypoxic tumor microenvironment (TME). Sonoporation, combining ultras...
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Healthcare Utilization and Its Correlates in Comorbid Type 2 Diabetes Mellitus and Generalized Anxiety Disorder
This study investigated the healthcare utilization and medical expenditure of type 2 diabetes mellitus (T2DM) patients with generalized anxiety disorder (GAD) and identified the associated factors. The healthc...
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Open AccessCritical roles of tubular mitochondrial ATP synthase dysfunction in maleic acid-induced acute kidney injury
Maleic acid (MA) induces renal tubular cell dysfunction directed to acute kidney injury (AKI). AKI is an increasing global health burden due to its association with mortality and morbidity. However, targeted t...
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Open AccessExamining arterial pulsation to identify and risk-stratify heart failure subjects with deep neural network
Hemodynamic parameters derived from pulse wave analysis have been shown to predict long-term outcomes in patients with heart failure (HF). Here we aimed to develop a deep-learning based algorithm that incorpor...
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Effects of Long-term Climate Change on Typhoon Rainfall Associated with Southwesterly Monsoon Flow near Taiwan: Mindulle (2004) and Morakot (2009)
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On the Phase Configurational Entropy of Dual-Phase γ/γ′ Multi-principal Element Alloys: A Case Study on the Al–Cu–Fe–Ni–Ti System
Configurational entropy is an important indicator of the formability of single solid solutions in multi-principal element alloys, typically estimated by using nominal compositions. However, nearly half of repo...
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Open AccessUrban people’s preferences for life-sustaining treatment or artificial nutrition and hydration in advance decisions
The Patient Right to Autonomy Act (PRAA), implemented in Taiwan in 2019, enables the creation of advance decisions (AD) through advance care planning (ACP). This legal framework allows for the withholding and ...