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Article
Open AccessHeat-related illness and dementia: a study integrating epidemiological and experimental evidence
Heat-related illness (HRI) is commonly considered an acute condition, and its potential long-term consequences are not well understood. We conducted a population-based cohort study and an animal experiment to ...
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Article
Health-related quality of life by veterans RAND 12 and healthcare resource utilization in cancer patients with sleep disorders: insights from the Medical Expenditure Panel Survey
This study aims to investigate the joint effects of cancer and sleep disorders on the health-related quality of life (HRQoL), healthcare resource utilization, and expenditures among US adults.
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Article
Open AccessAssociation between chronic pain and acute coronary syndrome in the older population: a nationwide population-based cohort study
Chronic pain (CP) may increase the risk of acute coronary syndrome (ACS); however, this issue in the older population remains unclear. Therefore, this study was conducted to clarify it.
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Article
Open AccessUsing artificial intelligence to predict adverse outcomes in emergency department patients with hyperglycemic crises in real time
Hyperglycemic crises are associated with high morbidity and mortality. Previous studies have proposed methods to predict adverse outcomes of patients in hyperglycemic crises; however, artificial intelligence (...
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Article
Open AccessEradication therapy may decrease the risk of immune thrombocytopenia after Helicobacter pylori infection: a retrospective cohort study in Taiwan
Helicobacter pylori (HP) eradication therapy (HPE) is recommended for patients with unexplained immune thrombocytopenia (ITP); however, the role of HPE in preventing ITP in patients with HP infection remains uncl...
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Article
Computerized tool and interdisciplinary care for older patients with delirium in the emergency department: a novel model in Taiwan
A computerized tool and interdisciplinary care were implemented to develop a novel model for older patients with delirium in the emergency department (ED).
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Open AccessAssociation between carbon monoxide poisoning and adrenal insufficiency: a nationwide cohort study
Carbon monoxide poisoning may damage the brain and adrenal glands, but it is unclear whether it is associated with adrenal insufficiency. We identified all COP patients diagnosed between 1999 and 2012 in Taiwa...
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Article
Interdisciplinary collaboration and computer-assisted home healthcare referral in the emergency department: a retrospective cohort study
Home healthcare (HHC) provides continuous care for disabled patients. However, HHC referral after the emergency department (ED) discharge remains unclear. Thus, this study aimed its clarification.
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Article
Open AccessAssociations between dietary patterns and stages of chronic kidney disease
Studies have revealed that patients with chronic kidney disease (CKD) have dietary patterns different from those of the general population. However, no studies have compared the dietary patterns of between pat...
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Article
Open AccessShort- and long-term recurrence of early-stage invasive ductal carcinoma in middle-aged and old women with different treatments
Most new cases and the highest mortality rates of breast cancer occur among middle-aged and old women. The recurrence rate of early-stage invasive ductal carcinoma (IDC) among women aged ≥ 50 years and receivi...
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Article
Open AccessPredicting outcomes in older ED patients with influenza in real time using a big data-driven and machine learning approach to the hospital information system
Predicting outcomes in older patients with influenza in the emergency department (ED) by machine learning (ML) has never been implemented. Therefore, we conducted this study to clarify the clinical utility of ...
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Article
Carbon monoxide-triggered health effects: the important role of the inflammasome and its possible crosstalk with autophagy and exosomes
Carbon monoxide (CO) has long been known as a “silent killer” because of its ability to bind hemoglobin (Hb), leading to reduced oxygen carrying capacity of Hb, which is the main cause of CO poisoning (COP) in...
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Article
Validation of shock index for predicting mortality in older patients with dengue fever
Older adults have a higher mortality for dengue fever (DF). However, the best method for predicting mortality is still unclear.
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Open AccessClinical physiological parameters for the prediction of gram-negative bacterial infection in the emergency department
Early detection and treatment of Gram-negative bacteria (GNB), major causative pathogens of sepsis (a potentially fatal condition caused by the body’s response to an infection), may benefit a patient’s outcome...
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Article
Open AccessImpact of carbon monoxide poisoning on the risk of breast cancer
Carbon monoxide (CO) is a toxic gas and an endogenous signaling molecule. Some studies involving cell lines have revealed the potential antibreast cancer effects of CO. Data on such effects in humans, however,...
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Article
Open AccessReal-time AI prediction for major adverse cardiac events in emergency department patients with chest pain
A big-data-driven and artificial intelligence (AI) with machine learning (ML) approach has never been integrated with the hospital information system (HIS) for predicting major adverse cardiac events (MACE) in...
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Article
Open AccessAssociation between exercise and health-related quality of life and medical resource use in elderly people with diabetes: a cross-sectional population-based study
Exercise improves glycemic control and functional capacity in elderly people with diabetes; however, its effect on health-related quality of life (HRQoL) and medical resource use remains unclear. This study ai...
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Article
Open AccessIschemia/reperfusion injured intestinal epithelial cells cause cortical neuron death by releasing exosomal microRNAs associated with apoptosis, necroptosis, and pyroptosis
To date, there is no good evidence that intestine epithelial cells (IEC) affected by ischemia/reperfusion (I/R) injury are able to cause cortical neuron injury directly. Additionally, it remains unclear whethe...
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Article
Comparison of the risk for dementia between physicians and the general population: a nationwide population-based cohort study
Physicians have better medical knowledge, which may decrease the risk of dementia; however, this issue remains unclear. This study was performed to clarify it.
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Article
Effects of Hyperbaric Oxygen Therapy on Acute Myocardial Infarction Following Carbon Monoxide Poisoning
Carbon monoxide poisoning (COP) may increase the risk of myocardial infarction. We conducted a study to investigate the effects of hyperbaric oxygen therapy (HBOT) on the risk. We used the Nationwide Poisoning...
