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  1. No Access

    Article

    D-Amino-acid-stimulated ethylene production in seed tissues

    Ethylene production by axial and cotyledonary tissues excised from Xanthium pennsylvanicum Wallr. seeds was markedly (up to 5-fold) stimulated by the D-isomers of phenylalanine, valine, leucine, threonine, methio...

    Shigeru Satoh, Yohji Esashi in Planta (1980)

  2. No Access

    Chapter

    S-Adenosylmethionine-Dependent Inactivation of 1-Aminocyclopropane-1-Carboxylate Synthase Isolated from Tomato Fruits

    1-Aminocyclopropane-1-carboxylate (ACC) synthase, which was partially purified from wounded tomato (Lycoperiscon esculentum Mill.) pericarp tissue, was inactivated by its substrate S-adenosyl-L-methionine (SAM) d...

    Shigeru Satoh, Shang Fa Yang in Biochemical and Physiological Aspects of E… (1989)

  3. No Access

    Article

    Effect of enalapril on Adriamycin-induced nephrosis

    Adriamycin induces proteinuria and glomerular changes in rats similar to those found in human focal segmental glomerulosclerosis (FSGS). Progression of this lesion may be slowed by use of angiotensin convertin...

    Kimberly C. Irwin, Ben H. Brouhard, Shigeru Satoh in Pediatric Nephrology (1992)

  4. No Access

    Article

    1,1-Dimethyl-4-(phenylsulfonyl)semicarbazide (DPSS) does not inhibit the in vitro activities of 1-aminocyclopropane-1-carboxylate (ACC) oxidase and ACC synthase obtained from senescing carnation Dianthus caryophyllus L.) petals

    The effects of 1,1-dimethyl-4-(phenylsulfonyl)semicarbazide (DPSS) on the in vitro activities of 1-aminocyclopropane-1-carboxylate (ACC) oxidase and ACC synthase isolated from senescing carnation petals were i...

    Shigeru Satoh, Naoko Oyamada, Toshihito Yoshioka, Naoki Midoh in Plant Growth Regulation (1997)

  5. No Access

    Article

    Induction by ozone of ethylene production and an ACC oxidase cDNA in rice (Oryza sativa L.) leaves

    Exposure to ozone at 1 µl l−1 for 6 h induced ethylene production in rice (Oryza sativa L. cv. Hitomebore) leaves. The stimulation of ethylene production was detectable 2 h after the start of the exposure to ozon...

    Takehiro Ohki, Hideki Matsui, Atsushi Nagasaka in Plant Growth Regulation (1999)

  6. No Access

    Article

    Circulating prostate-specific antigen mRNA during radical prostatectomy in patients with localized prostate cancer: with special reference to neoadjuvant hormonal therapy

    To determine the potential risk of hematogenous dissemination of prostate cancer cells during radical prostatectomy (RP), we investigated the pre- and intraoperative circulating prostate-specific antigen (PSA...

    Osamu Ogawa, Masanori Iinuma, Kazunari Sato, Ryusei Sasaki in Urological Research (1999)

  7. No Access

    Article

    Characteristics of the inhibitory action of 1,1-dimethyl-4-(phenylsulfonyl)semicarbazide (DPSS) on ethylene production in carnation (Dianthus caryophyllus L.) flowers

    1,1-Dimethyl-4-(phenylsulfonyl)semicarbazide (DPSS)inhibited ethylene productionin carnation flowers during natural senescence, butdid not inhibit the ethyleneproduction induced by exogenous ethylene in carnat...

    Tomoko Onoue, Mariko Mikami, Toshihto Yoshioka in Plant Growth Regulation (2000)

  8. No Access

    Article

    Hypermethylation at 9q32-33 tumour suppressor region is age-related in normal urothelium and an early and frequent alteration in bladder cancer

    Transcriptional silencing by CpG island hypermethylation of gene regulatory regions is one mechanism for inactivation of tumour suppressor genes. Chromosome 9q deletion is frequently found in transitional cell...

    Tomonori Habuchi, Takeshi Takahashi, Hideaki Kakinuma, Lizhong Wang in Oncogene (2001)

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    Article

    Stereoselective metabolism of rabeprazole-thioether to rabeprazole by human liver microsomes

    Rabeprazole is metabolized mainly non-enzymatically to rabeprazole-thioether. This in vitro study was designed to clarify the stereoselective oxidation mechanism and to identify the enzyme(s) involved in the m...

    Masatomo Miura, Shigeru Satoh, Hitoshi Tada in European Journal of Clinical Pharmacology (2006)

  10. No Access

    Article

    Transformation of carnation with genes related to ethylene production and perception: towards generation of potted carnations with a longer display time

    Potted carnation (Dianthus caryophyllus L. cv. Lillipot) plants were transformed with cDNAs for carnation 1-aminocyclopropane-1-carboxylate (ACC) synthase (DC-ACS1, s/aACS transgenes) or ACC oxidase (DC-ACO1, s/a...

    Tomoyuki Kinouchi, Reiko Endo, Atsushi Yamashita in Plant Cell, Tissue and Organ Culture (2006)

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    Article

    Influence of UGT1A8 and UGT2B7 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

    UGT1A8 and UGT2B7 are important uridine diphosphate-glucuronosyltransferase isoforms for the glucuronidation of mycophenolic acid (MPA). The aim of this investigation was to elucidate MPA pharmacokinetics in U...

    Hideaki Kagaya, Kazuyuki Inoue, Masatomo Miura in European Journal of Clinical Pharmacology (2007)

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    Article

    Influence of Cytochrome P450 (CYP) 3A5 Polymorphisms on the Pharmacokinetics of Lansoprazole Enantiomers in CYP2C19 Extensive Metaboliser Renal Transplant Recipients

    Background and objective: Lansoprazole is extensively metabolised by cytochrome P450 (CYP) 2C19 and CYP3A4. The purpose of this study was to evaluate the effects of CYP3A5 polymorphism (A6986G) o...

    Dr Masatomo Miura, Kazuyuki Inoue, Shigeru Satoh in Clinical Drug Investigation (2007)

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    Article

    Lymphatic invasion is a prognostic factor for bladder cancer treated with radical cystectomy

    We aimed to elucidate the significance of pathological prognostic factors in patients with bladder cancer treated with radical cystectomy and pelvic lymphadenectomy focusing on the association between lymphati...

    Yohei Horikawa, Teruaki Kumazawa in International Journal of Clinical Oncology (2007)

  14. No Access

    Article

    Anoxia-enhanced expression of genes isolated by suppression subtractive hybridization from pondweed (Potamogeton distinctus A. Benn.) turions

    Pondweed (Potamogeton distinctus A. Benn.), a monocot aquatic plant species, has turions, which are overwintering buds forming underground as an asexual reproductive organ. Turions not only survive for more than ...

    Taro Harada, Shigeru Satoh, Toshihito Yoshioka, Kimiharu Ishizawa in Planta (2007)

  15. No Access

    Article

    Influence of SLCO1B1, 1B3, 2B1 and ABCC2 genetic polymorphisms on mycophenolic acid pharmacokinetics in Japanese renal transplant recipients

    We investigated the association between mycophenolic acid (MPA) pharmacokinetics and organic anion-transporting polypeptide (OATP/SLCO)1B1, 1B3, 2B1 and multidrug resistance-association protein 2 (MRP2/ABCC2) gen...

    Masatomo Miura, Shigeru Satoh, Kazuyuki Inoue in European Journal of Clinical Pharmacology (2007)

  16. No Access

    Article

    Thrombotic microangiopathy develo** in early stage after renal transplantation with a high trough level of tacrolimus

    Thrombotic microangiopathy (TMA) is characterized clinically by hemolytic anemia, thrombocytopenia, and renal failure. Cyclosporine (CyA)-associated TMA is a well-documented complication, but tacrolimus (TAC)-...

    Mitsuru Saito, Shigeru Satoh, Hideaki Kagaya in Clinical and Experimental Nephrology (2008)

  17. Article

    Open Access

    A genetic polymorphism of the osteoprotegerin gene is associated with an increased risk of advanced prostate cancer

    The purpose of this study was to evaluate the role of osteoprotegerin gene (OPG) polymorphisms as genetic modifiers in the etiology of prostate cancer (PCa) and disease progression.

    Naofumi Narita, Takeshi Yuasa, Norihiko Tsuchiya, Teruaki Kumazawa in BMC Cancer (2008)

  18. No Access

    Article

    Suppressed Leaf Senescence in Chrysanthemum Transformed with a Mutated Ethylene Receptor GenemDG-ERS1(etr1-4)

    Previously, Narumi et al. (2005) generated chrysanthemum plants transformed with a mutated ethylene receptor gene (mDG-ERS1(etr1-4<), and showed that thein vitro plantlets of the transformants grown aseptically i...

    Shigeru Satoh, Masanobu Watanabe, Keiko Chisaka, Takako Narumi in Journal of Plant Biology (2008)

  19. Article

    Open Access

    Characterization of prostate cancer detected at repeat biopsy

    The aim of this study was to investigate the characteristics of prostate cancer patients who were diagnosed at repeat biopsy and compare them to non-cancerous patients or patients who were diagnosed at initial...

    Takeshi Yuasa, Norihiko Tsuchiya, Teruaki Kumazawa, Takamitsu Inoue in BMC Urology (2008)

  20. No Access

    Article

    CYP3A5 *1 allele associated with tacrolimus trough concentrations but not subclinical acute rejection or chronic allograft nephropathy in Japanese renal transplant recipients

    We assessed reported associations of CYP3A5 *1 allele with a delay in achieving target tacrolimus concentrations, and occurrence of biopsy-confirmed subclinical acute rejection (SAR) and chronic allograft nephrop...

    Shigeru Satoh, Mitsuru Saito, Takamitsu Inoue in European Journal of Clinical Pharmacology (2009)

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