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Article
COPD stage detection: leveraging the auto-metric graph neural network with inspiratory and expiratory chest CT images
Chronic obstructive pulmonary disease (COPD) is a common lung disease that can lead to restricted airflow and respiratory problems, causing a significant health, economic, and social burden. Detecting the COPD...
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Article
Open AccessAssociation of sodium-glucose cotransporter 2 inhibitors with risk of major adverse cardiovascular events in type 2 diabetes patients with acute coronary syndrome: a propensity score‑matched analysis
This study aimed to investigate the association of sodium-glucose cotransporter 2 inhibitors (SGLT2i) use with cardiovascular (CV) clinical outcomes in type 2 diabetes (T2D) patients with acute coronary syndro...
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Article
Transcriptomics and Metabolomics Unveil the Neuroprotection Mechanism of AnGong NiuHuang (AGNH) Pill Against Ischaemic Stroke Injury
As a famous prescription in China, AnGong NiuHuang (AGNH) pill exerts good neuroprotection for ischaemic stroke (IS), but its mechanism is still unclear. In this study, the neuroprotection of AGNH was evaluate...
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Article
Open AccessPien Tze Huang regulates phosphorylation of metabolic enzymes in mice of hepatocellular carcinoma
The Chinese medicine formula Pien Tze Huang (PZH) has been applied to the treatment of various diseases, the reported anti-tumor mechanisms included regulation of inflammation-associated cytokine secretion and...
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Article
Partial recovery of the left DLPFC-right insula circuit with reduced craving in abstinent heroin users: a longitudinal study
The phenomenon of brain recovery after long-term abstinence has been reported in substance use disorders. However, few longitudinal studies have been conducted to observe the potential recovery in heroin users...
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Article
Abnormal hippocampal substructure volume in insomnia disorder
To date, our understanding of the role of abnormal hippocampal volume in imaging studies of insomnia disorders (ID) has remained in apparent contradiction. Given that hippocampal function can be mapped to anat...
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Article
Disrupted frontostriatal connectivity in primary insomnia: a DTI study
Dysfunction of the sleep-wake transition is considered to be associated with the pathology of patients with primary insomnia (PI). Previous animal study had reported that brain circuits between the striatum an...
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Article
Impulsivity in heroin‐dependent individuals: structural and functional abnormalities within frontostriatal circuits
High levels of impulsivity are a risk factor for the initiation of heroin use and a core behavioral characteristic of heroin dependence. Impulsivity also contributes to the maintenance of drug use and hinders ...
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Article
Open AccessGenome-wide analysis of SET-domain group histone methyltransferases in apple reveals their role in development and stress responses
Histone lysine methylation plays an important role in plant development and stress responses by activating or repressing gene expression. Histone lysine methylation is catalyzed by a class of SET-domain group ...
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Article
Potential neural mechanism of single session transcranial magnetic stimulation on smoking craving
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Article
Experimental characterization of multi-nozzle atomization interference for dust reduction between hydraulic supports at a fully mechanized coal mining face
To analyze the distribution pattern concerning multi-nozzle interference spray particle granularity between hydraulic supports, the present study conducts atomization interference experimental characterization...
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Article
Correction: Corrigendum: RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functi...
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Article
Open AccessRILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking
The HOPS complex serves as a tethering complex with GEF activity for Ypt7p in yeast to regulate late endosomal membrane maturation. While the role of HOPS complex is well established in yeast cells, its functi...
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Chapter and Conference Paper
The Development of Remote Labor Training System for Rural Small Towns Based on MVC Model
In view of the characteristics of the rural labor force in China, a remote training system for small towns is developed based on B/S architecture and MVC model by using object-oriented and JSP technology on th...