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Article
Transperineal magnetic resonance imaging targeted biopsy versus transrectal route in the detection of prostate cancer: a systematic review and meta-analysis
Magnetic resonance imaging (MRI) has deeply altered the prostate biopsy strategy to detect prostate cancer. However, it is still debatable whether the detection rate differs between transrectal (TR) and transp...
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Article
Open AccessDiabetes and aortic dissection: unraveling the role of 3-hydroxybutyrate through mendelian randomization
In observational and experimental studies, diabetes has been reported as a protective factor for aortic dissection. 3-Hydroxybutyrate, a key constituent of ketone bodies, has been found to favor improvements i...
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Article
Open AccessThe implications of single-cell RNA-seq analysis in prostate cancer: unraveling tumor heterogeneity, therapeutic implications and pathways towards personalized therapy
In recent years, advancements in single-cell and spatial transcriptomics, which are highly regarded developments in the current era, particularly the emerging integration of single-cell and spatiotemporal tran...
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Article
Open AccessDevelopment of postoperative bronchopleural fistula after neoadjuvant immunochemotherapy in non-small cell lung cancer: case reports and review of the literature
The advent of immune checkpoint inhibitors has dramatically changed the treatment paradigm for advanced non-small-cell lung cancer (NSCLC). Due to the complexity and diversity of stage III disease, the inclusi...
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Article
Task planning of space debris removal based on a hierarchical exploration artificial bee colony algorithm
Space debris poses a potentially catastrophic risk to large-scale LEO constellations due to its substantial cascading effects, thereby rendering efficient and timely debris removal a critical research area in ...
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Article
Terrestrial laser scanning-assisted roughness assessment for initial support of railway tunnel
The assessment of initial support roughness is of utmost importance in ensuring waterproofing and structural safety in tunnel projects. However, existing measurement methods and evaluation systems fall short o...
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Chapter and Conference Paper
Study on the Coefficient of Recovery of Impact-Resistant Cushions for Rockfalls on Highways with Different Materials
Highways in the western mountains are often threatened by avalanches and rockfalls in mountainous areas with intricate geologic. It is an effective measure to prevent and control rockfall-threatening highways ...
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Chapter
Future Digital Twin in Infrastructure Management
In this chapter, “Future Digital Twin in Infrastructure Management,” discusses the advancements and potential future developments of digital twin technology in the field of infrastructure management. The chapt...
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Chapter
Digital Twins Technologies
This chapter of “Digital Twin Technologies in Transportation Infrastructure Management” focuses on Digital Twin technologies and their various aspects. The chapter begins by discussing the different types of D...
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Chapter
Digital Twin in TIM
This chapter of “Digital Twin Technologies in Transportation Infrastructure Management” focuses on the use of digital twin technology in TIM. The chapter begins with an introduction to digital twin in TIM, inc...
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Chapter
Digital Twins in Operation and Maintenance(O&P)
This chapter of “Digital Twin Technologies in Transportation Infrastructure Management” focuses on the role of Digital Twins in the operation and maintenance of transportation infrastructure. The chapter start...
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Chapter
Introduction to Digital Twin Technologies in Transportation Infrastructure Management (TIM)
This chapter of “Digital Twin Technologies in Transportation Infrastructure Management” provides an introduction to the concept of Digital Twin in the context of Infrastructure Management. The chapter begins b...
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Book
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Chapter
Transportation Infrastructure Management
This chapter of “Digital Twin Technologies in Transportation Infrastructure Management” explores Transportation Infrastructure Management (TIM) in detail. The chapter begins by providing an overview of the var...
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Chapter
Digital Twins in Design and Construction
Digital twins are gaining attention in the construction industry, as they offer several benefits such as reducing risks, improving quality, and enhancing productivity. This chapter explores the application of ...
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Article
Open AccessADP-dependent glucokinase controls metabolic fitness in prostate cancer progression
Cell metabolism plays a pivotal role in tumor progression, and targeting cancer metabolism might effectively kill cancer cells. We aimed to investigate the role of hexokinases in prostate cancer (PCa) and iden...
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Article
Open AccessPlacenta mesenchymal stem cell-derived extracellular vesicles alleviate liver fibrosis by inactivating hepatic stellate cells through a miR-378c/SKP2 axis
Extracellular vesicles derived from mesenchymal stem/stromal cells (MSCs) have shown therapeutic effects on liver fibrosis. This study aimed to evaluate the effects of extracellular vesicles from placenta-deri...
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Article
Open AccessStatus of diagnosis and preventative treatment for primary headache disorders: real-world data of unmet needs in China
Headache disorders are widely prevalent and pose a considerable economic burden on individuals and society. Globally, misdiagnosis and inadequate treatment of primary headache disorders remain significant chal...
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Article
Open AccessAssociation between nickel exposure and body compositions in the United States: a population-based cross-sectional study
Increasing body fat or decreasing muscle and bone mass were associated with worse health outcomes in the adult population. The effects of nickel exposure on body composition are not known. The aim of the curre...
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Article
Open AccessFunctional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia
The genus Salvia L. (Lamiaceae) comprises myriad distinct medicinal herbs, with terpenoids as one of their major active chemical groups. Abietane-type diterpenoids (ATDs), such as tanshinones and carnosic acids, ...
