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1,015 Result(s)
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Article
Open AccessThe biological characteristics and infection dynamics of a novel H3N2 canine influenza virus genotype in beagles
The canine influenza virus (CIV) outbreak has garnered considerable attention as it poses a significant threat to dog health. During the H3N2 CIV evolution in beagles, the virus formed a new clade after 2019 a...
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Remodel the perifollicular microenvironment via Minoxidil-loaded microneedle patch and cold atmospheric plasma for treating androgenetic alopecia
Androgenetic alopecia (AGA) is a chronic and progressive form of hair loss characterized by vascular degeneration in the perifollicular microenvironment, leading to cell apoptosis and eventual loss of hair fol...
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Enzyme-activatable disk-shaped nanocarriers augment tumor permeability for breast cancer combination therapy
Unique physiopathological characteristics of tumor tissues impose obstacles to the sufficient penetration of traditional nanomedicines, resulting in undesirable drug delivery efficacy and therapeutic outcomes....
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Silicon-coated multi-walled carbon nanotube (MWCNT) tissues as flexible free-standing anodes for advanced Li-ion batteries
Further progress in flexible electronic devices, such as soft electronics, rollable and wearable displays, and bendable smartphones, implies essential evolution in the field of flexible energy storage devices....
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Microstructural and hemodynamic changes in the fundus after pars plana vitrectomy for different vitreoretinal diseases
Pars plana vitrectomy is the standard treatment for several vitreoretinal diseases. Continuous improvements in ophthalmic surgical techniques have led to excellent postoperative recovery of the anatomic struct...
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Article
Open AccessHealth care workers’ self-perceived meaning of residential care work
Attracting and supporting a sustainable long-term care (LTC) workforce has been a persistent social policy challenge across the globe. To better attract and retain a sustainable LTC workforce, it is necessary ...
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Article
The effect of temperature on the roll graphite films derived from Kapton polyimide films
Aromatic polyimide films are widely used in high-tech fields due to their excellent combination of thermal, mechanical, and electrical properties. These films serve as precursors for the preparation of high th...
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Open AccessAssociation analyses of apolipoprotein E genotypes and cognitive performance in patients with Parkinson’s disease
Cognitive impairment is a common non-motor symptom of Parkinson’s disease (PD). The apolipoprotein E (APOE) ε4 genotype increases the risk of Alzheimer’s disease (AD). However, the effect of APOEε4 on cognitiv...
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Effects of belimumab on the lipid profile in systemic lupus erythematosus patients: an observational study
This study is asked to investigate the effects of belimumab on the lipid profile in systemic lupus erythematosus (SLE) patients. Forty-one SLE patients who received at least 6 months of belimumab treatment wer...
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Open AccessCoHIT: a one-pot ultrasensitive ERA-CRISPR system for detecting multiple same-site indels
Genetic testing is crucial for precision cancer medicine. However, detecting multiple same-site insertions or deletions (indels) is challenging. Here, we introduce CoHIT (Cas12a-based One-for-all High-speed Is...
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Molecular mechanism of Saikosaponin-d in the treatment of gastric cancer based on network pharmacology and in vitro experimental verification
The study aimed to utilize network pharmacology combined with cell experiments to research the mechanism of action of Saikosaponin-d in the treatment of gastric cancer. Drug target genes were obtained from the...
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Graphene membranes with pyridinic nitrogen at pore edges for high-performance CO2 capture
Membranes based on a porous two-dimensional selective layer offer the potential to achieve exceptional performance to improve energy efficiency and reduce the cost for carbon capture. So far, separation from t...
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Article
BDNF-VGF Pathway Aggravates Incision Induced Acute Postoperative Pain via Upregulating the Neuroinflammation in Dorsal Root Ganglia
Approximately one-third of postoperative patients are troubled by postoperative pain. Effective treatments are still lacking. The aim of this study is to investigate the role of brain-derived neurotrophic fact...
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Magnetic resonance–enhanced high-resolution three-dimensional water-selective cartilage sequence visualization of hip vessels in children
Hip vessel examination provides key information on many hip-related pediatric diseases, and it has an important role in the evaluation of femoral head (FH) blood supply and diagnosis of avascular necrosis (AVN...
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Open AccessEffects of Dietary Valine Chelated Zinc Supplementation on Growth Performance, Antioxidant Capacity, Immunity, and Intestine Health in Weaned Piglets
This study was conducted to investigate the effects of dietary valine chelated zinc (ZnVal) supplementation on growth performance, antioxidant capacity, immunity, and intestine health in weaned piglets. A tota...
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Article
Resveratrol ameliorates DSS-induced ulcerative colitis by acting on mouse gut microbiota
Ulcerative colitis (UC) is a multi-faceted, recurrent immune disorder caused by dextran sulfate sodium (DSS). The intestinal microbiota has multiple functions in the host, so UC requires long-term potent medic...
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Article
Cushioning Performance of a Novel Polyurethane Foam Material Applied in Fragile Packaging
For fragile products, packaging requires cushioning protection to prevent irreversible damage from accidental falls, transportation impacts, and other causes. The new polyurethane foam (PUF) material demonstra...
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Open AccessProteomic analysis of cardiorespiratory fitness for prediction of mortality and multisystem disease risks
Despite the wide effects of cardiorespiratory fitness (CRF) on metabolic, cardiovascular, pulmonary and neurological health, challenges in the feasibility and reproducibility of CRF measurements have impeded i...
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Article
Mammalian IRE1α dynamically and functionally coalesces with stress granules
Upon endoplasmic reticulum (ER) stress, activation of the ER-resident transmembrane protein kinase/endoribonuclease inositol-requiring enzyme 1 (IRE1) initiates a key branch of the unfolded protein response (U...
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Targeting the Ferroptosis and Endoplasmic Reticulum Stress Signaling Pathways by CBX7 in Myocardial Ischemia/reperfusion Injury
Ferroptosis and endoplasmic reticulum stress (ERS) are common events in the process of myocardial ischemia/reperfusion injury (IRI). The suppression of chromobox7 (CBX7) has been reported to protect against is...