53 Result(s)
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Sheryl L. Rifas-Shiman
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Article
Metabolomic signatures for blood pressure from early to late adolescence: findings from a U.S. cohort
Metabolite signatures for blood pressure (BP) may reveal biomarkers, elucidate pathogenesis, and provide prevention targets for high BP. Knowledge regarding metabolites associated with BP in adolescence remain...
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Open AccessAssociations of prenatal maternal depressive symptoms with cord blood glucocorticoids and child hair cortisol levels in the project viva and the generation R cohorts: a prospective cohort study
Prior studies have reported conflicting results regarding the association of prenatal maternal depression with offspring cortisol levels. We examined associations of high levels of prenatal depressive symptoms...
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Open AccessAnalysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude
Seasonal variations in environmental exposures at birth or during gestation are associated with numerous adult traits and health outcomes later in life. Whether DNA methylation (DNAm) plays a role in the molec...
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Open AccessAuthor Correction: Genetic effects on the timing of parturition and links to fetal birth weight
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Open AccessDNA methylation age at birth and childhood: performance of epigenetic clocks and characteristics associated with epigenetic age acceleration in the Project Viva cohort
Epigenetic age acceleration (EAA) and epigenetic gestational age acceleration (EGAA) are biomarkers of physiological development and may be affected by the perinatal environment. The aim of this study was to e...
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Open AccessGenetic effects on the timing of parturition and links to fetal birth weight
The timing of parturition is crucial for neonatal survival and infant health. Yet, its genetic basis remains largely unresolved. We present a maternal genome-wide meta-analysis of gestational duration (n = 195,55...
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Open AccessAdolescent overeating and binge eating behavior in relation to subsequent cardiometabolic risk outcomes: a prospective cohort study
Binge eating disorder is bidirectionally associated with obesity and with metabolic syndrome. It is less clear whether overeating and binge eating, or overeating with loss of control, also predicts metabolic r...
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Open AccessAssociation of total lifetime breastfeeding duration with midlife handgrip strength: findings from Project Viva
Lactation has long term effects on maternal health, but the relationship between lactation and long-term handgrip strength, a marker of musculoskeletal function and healthy aging, has not been explored.
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Open AccessHistory of infertility and pregnancy outcomes in Project Viva: a prospective study
Infertility has been associated with the risk of adverse pregnancy outcomes. It is not clear whether infertility and underlying causes of infertility or the use of medically assisted reproduction (MAR) therapi...
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Open AccessLongitudinal associations of DNA methylation and sleep in children: a meta-analysis
Sleep is important for healthy functioning in children. Numerous genetic and environmental factors, from conception onwards, may influence this phenotype. Epigenetic mechanisms such as DNA methylation have bee...
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Open AccessMeta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills
Cognitive skills are a strong predictor of a wide range of later life outcomes. Genetic and epigenetic associations across the genome explain some of the variation in general cognitive abilities in the general...
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Open AccessCesarean delivery and metabolic health and inflammation biomarkers during mid-childhood and early adolescence
We assessed differences in plasma levels of metabolic health and inflammation biomarkers during mid-childhood and early adolescence between children born by cesarean section vs. vaginal delivery.
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Associations of maternal non-nutritive sweetener intake during pregnancy with offspring body mass index and body fat from birth to adolescence
The evidence that maternal non-nutritive sweetener (NNS) intake during pregnancy increases childhood obesity risk is conflicting. A potential reason for this is that all prior studies examined childhood body m...
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Open AccessPrenatal metal exposure, cord blood DNA methylation and persistence in childhood: an epigenome-wide association study of 12 metals
Prenatal exposure to essential and non-essential metals impacts birth and child health, including fetal growth and neurodevelopment. DNA methylation (DNAm) may be involved in pathways linking prenatal metal ex...
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Maternal anxiety during pregnancy and newborn epigenome-wide DNA methylation
Maternal anxiety during pregnancy is associated with adverse foetal, neonatal, and child outcomes, but biological mechanisms remain unclear. Altered foetal DNA methylation (DNAm) has been proposed as a potenti...
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Open AccessDNA methylation architecture of the ACE2 gene in nasal cells of children
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has led to the global coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 enters cells via angiotensin-Converting Enzyme 2 (ACE2) receptors, hi...
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Mode of delivery, type of labor, and measures of adiposity from childhood to teenage: Project Viva
Cesarean delivery has been linked with childhood obesity. Few studies have examined if this association is attenuated if there is labor prior to delivery. The objective of this current analysis was to examine ...
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Privacy-protecting multivariable-adjusted distributed regression analysis for multi-center pediatric study
Privacy-protecting analytic approaches without centralized pooling of individual-level data, such as distributed regression, are particularly important for vulnerable populations, such as children, but these m...
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Article
Neonatal Thyroxine, Maternal Thyroid Function, and Cognition in Mid-childhood in a US Cohort
Examine the associations of maternal thyroid hormones, maternal dietary information, and newborn T4 levels with cognitive outcomes in mid-childhood.
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Open AccessEpigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated...
