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  1. Article

    Open Access

    Clinical and analytical comparison of six Simoa assays for plasma P-tau isoforms P-tau181, P-tau217, and P-tau231

    Studies using different assays and technologies showed highly promising diagnostic value of plasma phosphorylated (P-)tau levels for Alzheimer’s disease (AD). We aimed to compare six P-tau Simoa assays, includ...

    Sherif Bayoumy, Inge M. W. Verberk, Ben den Dulk… in Alzheimer's Research & Therapy (2021)

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  2. Article

    Open Access

    Sensitive and quantitative detection of cardiac troponin I with upconverting nanoparticle lateral flow test with minimized interference

    Measurement of cardiac troponin I (cTnI) should be feasible for point-of-care testing (POCT) to diagnose acute myocardial infarction (AMI). Lateral flow immunoassays (LFIAs) have been long implemented in POCT ...

    Sherif Bayoumy, Iida Martiskainen, Taina Heikkilä, Carita Rautanen… in Scientific Reports (2021)

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  3. Article

    Open Access

    Glycovariant-based lateral flow immunoassay to detect ovarian cancer–associated serum CA125

    Cancer antigen 125 (CA125) is a widely used biomarker in monitoring of epithelial ovarian cancer (EOC). Due to insufficient cancer specificity of CA125, its diagnostic use is severely compromised. Abnormal gly...

    Sherif Bayoumy, Heidi Hyytiä, Janne Leivo, Sheikh M. Talha… in Communications Biology (2020)

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