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Article
Preliminary establishment and validation of the inversion method for growth and remodeling parameters of patient-specific abdominal aortic aneurysm
Traditional medical imaging and biomechanical studies have challenges in analyzing the long-term evolution process of abdominal aortic aneurysm (AAA). The homogenized constrained mixture theory (HCMT) allows f...
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Article
Morphology Optimization of Leaflet for Surgical Reconstruction of the Aortic Valve: In Vitro Test and Simulation-Based DOE Study
This study was to evaluate the impact of leaflet trimming strategy on the hemodynamic behaviors of the aortic valve after reconstructive surgery, and give recommendations based on design of experiment (DOE) an...
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Article
Discrimination of intracranial aneurysm rupture status: patient-specific inflow boundary may not be a must-have condition in hemodynamic simulations
Computational fluid dynamics (CFD) are important in evaluating the hemodynamics of intracranial aneurysm rupture, and the setting of inflow boundary conditions is critical. We evaluated intracranial aneurysm h...
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Article
Open AccessEfficient simulation of a low-profile visualized intraluminal support device: a novel fast virtual stenting technique
The low-profile visualized intraluminal support (LVIS) stent has become a promising endovascular option for treating intracranial aneurysms. To achieve better treatment of aneurysms using LVIS, we developed a ...
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Article
Open AccessPhantom-based experimental validation of fast virtual deployment of self-expandable stents for cerebral aneurysms
Endovascular intervention using a stent is a mainstream treatment for cerebral aneurysms. To assess the effect of intervention strategies on aneurysm hemodynamics, we have developed a fast virtual stenting (FV...
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Article
Open AccessComputational fluid dynamics analysis on recurrence of simple coiling intracranial aneurysms with remnant neck
Hemodynamic factors are considered to play an important role in the initiation and recurrence of cerebral aneurysms. However, hemodynamic characteristics leading to the recurrence of aneurysms is not well reco...
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Article
Open AccessFlow diverter effect of LVIS stent on cerebral aneurysm hemodynamics: a comparison with Enterprise stents and the Pipeline device
The aim of this study was to quantify the effect of the new Low-profile Visualized Intraluminal Support (LVIS®D) device and the difference of fluid diverting effect compared with the Pipeline device and the En...
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Article
Hemodynamic Alterations for Various Stent Configurations in Idealized Wide-neck Basilar Tip Aneurysm
Stent-assisted coiling technology is widely used in the treatment of intracranial aneurysms. However, differences among various stent configurations have not been fully characterized. This study investigates t...
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Article
Hemodynamic alterations after stent implantation in 15 cases of intracranial aneurysm
Stent-assisted coiling technology has been widely used in the treatment of intracranial aneurysms. In the current study, we investigated the intra-aneurysmal hemodynamic alterations after stent implantation an...
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Article
Open AccessInfluence of morphology and hemodynamic factors on rupture of multiple intracranial aneurysms: matched-pairs of ruptured-unruptured aneurysms located unilaterally on the anterior circulation
The authors evaluated the impact of morphological and hemodynamic factors on the rupture of matched-pairs of ruptured-unruptured intracranial aneurysms on one patient’s ipsilateral anterior circulation with 3D...
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Article
Hemodynamic performance of coil embolization and stentassisted coil embolization treatments: a numerical comparative study based on subject-specific models of cerebral aneurysms
Hemodynamic characteristics such as blood velocity, blood pressure, flow im**ement, wall shear stress and oscillatory shear index are considered to play important roles in the initiation, growth, rupture and...
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Article
The effect of aneurismal-wall mechanical properties on patient-specific hemodynamic simulations: two clinical case reports
Hemodynamic factors such as the wall shear stress play an important role in the pathogenesis and treatment of cerebral aneurysms. In present study, we apply computational fluid–structure interaction analyses o...
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Chapter and Conference Paper
A Lumped Parameters Dynamic Model for Cerebral Circulation
A lumped parameters dynamic model for cerebral blood circulation is constructed according to the hydrodynamic model, and the simulations prove the validity of this model. Given the values of the parameters and...
