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    Article

    MUC1* is a determinant of trastuzumab (Herceptin) resistance in breast cancer cells

    In the United States, 211,000 women are diagnosed each year with breast cancer. Of the 42,000 breast cancer patients who overexpress the HER2 growth factor receptor, <35% are responsive to treatment with the H...

    Shawn P. Fessler, Mark T. Wotkowicz… in Breast Cancer Research and Treatment (2009)

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    Article

    Involvement of caspase-cleaved and intact adaptor protein 1 complex in endosomal remodeling in maturing dendritic cells

    The involvement of the tetrameric adaptor protein 1 (AP-1) complex in protein sorting in intracellular compartments is not yet completely defined. Here we report that in immature dendritic cells, the β1- and γ...

    Laura Santambrogio, Ilaria Potolicchio, Shawn P Fessler… in Nature Immunology (2005)