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Open AccessScreening for frailty and its association with activities of daily living, cognitive impairment, and falls among community-dwelling older adults in China
Frailty is a prevalent geriatric condition that significantly impacts the health of older adults. This study aimed to examine the prevalence of frailty among older Chinese adults aged ≥ 65 years and to assess ...
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Article
The correlation between serum 1, 5-anhydroglucitol and β-cell function in Chinese adults with different glucose metabolism statuses
Serum 1, 5-AG is a glycaemic marker reflecting control and fluctuations of short-term glucose. To reveal the relationship between 1, 5-AG with β-cell function, we investigated a certain number of Chinese adult...
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Article
Fasting plasma glucose and 2-h postprandial plasma glucose characteristics in a large multi-ethnic Chinese population
During an oral glucose tolerance test (OGTT), typically fasting plasma glucose is lower than 2-h postprandial plasma glucose. However, postprandial plasma glucose (PPG) levels lower than fasting plasma glucose...
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Article
Open AccessEfficacy and Safety of Niraparib as First-Line Maintenance Treatment for Patients with Advanced Ovarian Cancer: Real-World Data from a Multicenter Study in China
Poly (ADP-ribose) polymerase (PARP) inhibitors are a new maintenance therapy option for patients with ovarian cancer (OC).
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Article
Effects of peer support and mobile application-based walking programme on physical activity and physical function in rural older adults: a cluster randomized controlled trial
To assess the effectiveness of a 3-month peer support and mobile application-based walking programme on physical activity and physical function in rural older Chinese adults.
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Article
Investigation of 1H nuclear magnetic resonance relaxometry to screen metabolic syndrome and diabetes
The purpose of this study was to investigate and compare the abilities of 1H nuclear magnetic resonance (NMR) transverse relaxation constant time (T2) and longitudinal relaxation constant time (T1) to screen peop...
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Article
Novel clusters of newly-diagnosed type 2 diabetes and their association with diabetic retinopathy: a 3-year follow-up study
Cluster analysis may assist in stratifying heterogeneous clinical presentations of type 2 diabetes (T2D). However, the association of cluster-based subgroups with diabetes-related outcomes such as diabetic ret...
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Open AccessMicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway
Type 2 diabetes is associated with a reduction in skeletal muscle mass; however, how the progression of sarcopenia is induced and regulated remains largely unknown. We aimed to find out whether a specific micr...
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Article
Increased waist-to-hip ratio is associated with decreased urine glucose excretion in adults with no history of diabetes
Promoting urine glucose excretion (UGE) is an attractive approach for the treatment of diabetes. Obesity is associated with increased risk for type 2 diabetes. This study was aimed to investigate the associati...
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Article
Efficacy of urinary glucose for diabetes screening: a reconsideration
Previous studies indicated that urinary glucose (UG) had a limited efficacy in diabetes screening. This study was designed to have a re-evaluation of its efficacy, taking into consideration the collection meth...
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Article
Open AccessExercise training and endothelial function in patients with type 2 diabetes: a meta-analysis
Exercise training is considered a cornerstone in the management of type 2 diabetes, which is associated with impaired endothelial function. However, the association of exercise training with endothelial functi...
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Open AccessEffects of resveratrol on glucose control and insulin sensitivity in subjects with type 2 diabetes: systematic review and meta-analysis
Although the regular consumption of resveratrol has been known to improve glucose homeostasis and reverse insulin resistance in type 2 diabetes mellitus (T2DM), the reported results are inconsistent. Thus, we ...
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Article
Chronic Exercise Training and Circulating Irisin in Adults: A Meta-Analysis
Irisin is a newly discovered hormone that is proposed to be a promising therapeutic target in obesity and type 2 diabetes. It has received remarkable attention recently, while inconsistent results have been sh...
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Open AccessStep counter use in type 2 diabetes: a meta-analysis of randomized controlled trials
While step counter use has become popular among type 2 diabetes (T2D) patients, its effectiveness in increasing physical activity (PA) and improving glycemic control has been poorly defined. The aim of this me...